W e have made a retrospective review of 185 cemented Charnley total hip arthroplasties performed between 1970 and 1974 to determine the relationships between radiological variables and failure of the femoral and acetabular components. We measured the acetabular wear, the orientation of the cup, the thickness and consistency of acetabular and femoral cement mantles, radiolucency and femoral alignment. The mean follow-up was for 11.7 years. Femoral loosening was demonstrable radiologically in 15 hips (8.1%), ten (5.4%) of which were revised during the period of follow-up. Only when the first postoperative radiograph showed a thin cement mantle in Gruen zone 5 was there a significant association with failure of the femoral component. There were 12 loose acetabular components (6.5%), nine (4.8%) of which were revised. When the initial radiograph after operation showed radiolucency in DeLee and Charnley zone 1, the incidence of acetabular loosening was 28.21%. If such radiolucency was not present, the incidence of acetabular loosening was only 0.69%. Our findings emphasise the importance of careful cementing.

We have made a retrospective review of 185 cemented Charnley total hip arthroplasties performed between 1970 and 1974 to determine the relationships between radiological variables and failure of the femoral and acetabular components. We measured the acetabular wear, the orientation of the cup, the thickness and consistency of acetabular and femoral cement mantles, radiolucency and femoral alignment. The mean follow-up was for 11.7 years. Femoral loosening was demonstrable radiologically in 15 hips (8.1%), ten (5.4%) of which were revised during the period of follow-up. Only when the first postoperative radiograph showed a thin cement mantle in Gruen zone 5 was there a significant association with failure of the femoral component. There were 12 loose acetabular components (6.5%), nine (4.8%) of which were revised. When the initial radiograph after operation showed radiolucency in DeLee and Charnley zone 1, the incidence of acetabular loosening was 28.21%. If such radiolucency was not present, the incidence of acetabular loosening was only 0.69%. Our findings emphasise the importance of careful cementing.

Introduction: Regenerative peripheral nerve interfaces (RPNI) are used to transduce motor nerve signals to and electrical sensory signals from a robotic arm. Quanti cation of sensory feedback is essential to assessment of closed loop neural continuity. Von Frey (VF)  lament testing has traditionally been used clinically for this purpose but has not been validated in the rodent. Our purpose was to (a) determine the ideal, 8- lament range for VF sensation measurements in the ankle and thigh of the rat, (b) determine the reliability at both locations and (c) apply the test in experimental studies of Mixed Nerve (MN) and Sensory Nerve (SN) RPNIs.

Objective:To determine the effect of axonal reconnection after nerve transection injury, with the membrane fusogen polyethylene glycol (PEG), and the antioxidant methylene blue (MB), on functional recovery.Methods: Animals were subjected to sciatic nerve transection followed by: no repair; PEG alone; suture alone; suture+PEG; and suture+PEG/MB. Compound action potentials (CAPs) were measured from the Sprague Dawley rat sciatic nerve: before transection; after transection; and after repair. Ex vivo nerve dye diffusion studies were performed to assess axonal continuity. Histological parameters of nerve regeneration including: nerve fiber counts; axon/fiber diameter; g-ratio, and myelin thickness were measured 5 mm proximal and distal to the repair at 1, 2, 3 and 12 weeks. Weekly hindlimb behavioral assessments were undertaken for 12 weeks with Sciatic Functional Index (SFI); and Foot Fault testing (FF).