Carpal Tunnel Syndrome results in considerable discomfort and pain, limitation of activities of daily living, loss of sleep and work disability. Carpal tunnel Syndrome is more frequent in pregnancy because the systemic process increases the extra capsular fluid retention by the hormone Prolactin and produce soft tissue swelling in the later stages (third trimester) of their pregnancies. Many therapies have been advocated for treating the carpal tunnel syndrome including Mobilizations, nerve gliding, tendon gliding, Ultrasound, icing, Massaging, Elevating the arm or flicking, Neural mobilization, wrist splints and invasive treatments like injecting corticosteroids in the carpal tunnel and eventually releasing the median nerve by surgery.etc. Women experience pregnancy several times, and if they acquire CTS, invasive treatments cannot be used, and pregnancy increases the probability of reoccurrence of CTS in the next pregnancy with higher intensity. So it is necessary to use non-invasive treatment methods. The disease is becoming very common nowadays as most of the population is engaged in computer work by some means especially the IT ladies who always use the conventional mouse for their work with the PC. One of the non invasive method of using the wearable device (wearable glove mouse) along with the tendon and nerve gliding exercises prescribed by the physiotherapists improves the condition. The occurrence of CTS is diagnosed by positive Tinel’s sign and positive Phalens test. This work tries to give possible non invasive solution for the CTS during pregnancy for IT women professionals and the relief of symptoms is measured with the help of VAS Scale, Functional Status Scale.