The variable expression of congenital CNS abnormalities makes their antenatal ultrasound diagnosis extremely difficult. Clinical decisions depend on ultrasound diagnosis; therefore, accurate antenatal diagnosis is imperative. A diagnostic algorithm based on ultrasonic demonstration of fetal cranial structures altered in congenital CNS abnormalities was constructed and applied retrospectively to 40 patients with clinicopathologic follow‐up adequate to define the cranial abnormality. Using the algorithm our diagnosis was correct in 37/40 (92 per cent) compared with 30/40 (75 per cent) without its use. The algorithm was highly accurate in the diagnosis of hydrocephalus (13/14), anencephaly/amniotic band syndrome (13/13), and holoprosencephaly (8/8). A wide spectrum of CNS abnormalities can be accurately diagnosed by ultrasonography in the antenatal period by the application of our algorithm.

As more sophisticated ultrasound instrumentation has become available, more complete and detailed examinations, including computer-manipulated data sheets, have been demanded by referring clinicians. In order to fill the clinical need, many suppliers have designed and promoted computer systems of unfortunately prohibitive costs. The purpose of this paper is to demonstrate the simplicity of designing a personally tailored data sheet and ease of programming one of the current commercially available microcomputers to perform the manipulations. Their use is outlined and encouraged.

BackgroundThe reported data of HIV + pregnant women in Latin America (LA) is scarce. Given the political and social changes that have occurred in recent years, Chile has had to face immigration as a recent phenomenon. Based on this, the objective of this analysis was to determine the baseline characteristics, virological during pregnancy and postpartum, and the impact of immigration on adult women infected with HIVMethodsThe registry of HIV + pregnant women of Fundación Arriarán was analyzed since 2006. The baseline characteristics,undetectability at delivery, vertical transmission and retention were determined.Estimators as mean and median,standard deviation and interquartile range; absolute and relative frequencies were used and for the bivariate analysis the t-test and chi2,Mann–Whitney and Fisher’s exact. For follow-up, the Kaplan–Meier method was used.ResultsA total of 214 pregnancies in 198 HIV + women were included. A 54% of foreigners (of Haitian predominance) was found, 2/3 of the foreigners were enrolled after 2016. A 73% was diagnosed with HIV at the time of pregnancy. Average age was 28.6 years. Baseline CD4 cell count was 396 cel/mm3. A 7.7% were admitted with advanced pregnancy and 4.6% had a history of drug addiction. None of these variables had significant differences between both groups. The variables of gestational age at admission (15 vs. 21; P < 0.001), gestational age at the beginning of therapy (18 vs. 21; P < 0.001), CDC stage and baseline viral load (9750 vs. 644 copies/mL;P < 0.001) were statistically significant between Chileans and foreigners. 58% of the patients achieved undetectability at the time of delivery without differences between both groups. (55% vs. 63%; p0.42) Almost 90% of women with detectable viral load at delivery was less than 1000 copies/mL (88,9%). 93% received full vertical transmission protocol and the prematurity rate was 16.6%. The vertical transmission was 2.6% without differences between nationals and foreigners. In the postpartum follow-up,70% were retained, 73% of them undetectable on the latest follow-up visit.ConclusionDespite the cultural and language limitations, foreign patients maintained a compliance similar to those of Chile, achieving a low transmission rate vertical and good adherence to postpartum controls.Disclosures All authors: No reported disclosures.