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Novel glycopolymers have been synthesized from ethylene-vinyl alcohol, EVOH, copolymers activated with 4-nitrophenyl carbonate groups and subsequent coupling reaction with distinct diaminobutylsaccharides. The structure of the resulting glycopolymers has been confirmed by FTIR and (1)H and (13)C NMR. In addition, their thermal transitions and degradability have been examined, as well as their rheological behavior in bulk and in water solution. Those glycopolymers that are water-soluble undergo self-association processes and lead to the formation of temperature-induced reversible networks. Furthermore, their affinity to lectins, in particular to Concanavalin A and Ricinus communis Agglutinin, has also been evaluated, showing large and specific interaction.

Ethylene-vinyl alcohol copolymers, EVOH, with two different vinyl alcohol compositions have been functionalized with carboxylic acid groups by reaction with phthalic anhydride. Later on, the coupling reaction of three aminosaccharides (D-(þ)-glucosamine, D-(þ)-galactosamine, and D-(þ)-mannosamine) to functionalized EVOH copolymers has been carried out in dimethyl sulfoxide at 70 C to achieve water soluble glycopolymers. The structure of the resulting functionalized copolymers and the new glycopolymers was confirmed by 1 H and 13 C NMR. Likewise, the thermal behavior of glycopolymers has been performed by differential scanning calorimetry and thermal gravimetric analysis. In addition, their affinity to lectins, specifically to Concanavalin A and Ricinus Communis Agglutinin, has been evaluated. V

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