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Ten different human tumors (two soft tissue sarcomas, seven adenocarcinomas of the colon and stomach and, one squamous cell carcinoma of the lung) were implanted s.c. in thymus-aplastic mice and retransplanted over several generations. In 40 animals, the tumors were studied by microangiography and microscopy and classified according to angiographic tumor criteria. Tumor transplants always revealed similar angiographic patterns. The microscopic results presented a good correlation with the roentgenologic findings. The microstructure of the tumor vessels and lacunes are analyzed and discussed. The nude mice model is well suitable for the research of human tumors.

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