The paper presents the results that allowed obtaining the dependence of laminar flame propagation speed Sl on the equivalence ratio for a wide range of pressures and temperatures during methane combustion. A literature review was carried out to summarize the experimental data on the measurement of the Sl. The Sl was calculated using a kinetic mechanism GRI 3.0 within the required pressure and temperature range. The calculation results were generalized in the MATLAB software product to verify the Sl power dependencies on pressure and initial temperature. The results of calculation on the basis of the obtained approximating dependence were compared with the experimental data and results obtained by other authors. It was found that the exponents of power for the dependency on pressure and temperature are described not by constants or linear relations, but by second-degree equations on the fuel-air ratio. The results can be used in three-dimensional simulation of combustion processes and in calculations performed using engineering practices.