Aim. To evaluate the effects of acupuncture and transcutaneous electric nerve stimulation (TENS) applications on the quantitative electroencephalography (qEEG) changes and to evaluate their therapeutic effects in patients with fibromyalgia syndrome (FMS). The study included 42 patients with FMS and 21 healthy volunteers. The patients were randomly assigned to two groups (n=21 in each) to undergo either TENS or acupuncture application. In both acupuncture and TENS groups, baseline electroencephalography (EEG) recording was performed for 10 min and, then, TENS or acupuncture was performed for 20 min, followed by another 10 min EEG recording. Baseline qEEG findings of FMS patients in the TENS and acupuncture groups were similar. Delta and theta powers over the frontal region of FMS patients were lower than controls. Theta powers of right posterior region were also lower than controls. In the TENS group, after the treatment, an increase was observed in the alpha power of the left anterior region as well as a decrease in pain scores. In the acupuncture group, an increase was determined in the alpha power of the right and left posterior regions as well as a decrease in pain score after the treatment. The power of low- and moderate-frequency waves on resting EEG was decreased in the patients with FMS. Decreased pain and increased inhibitor activity were found on qEEG after TENS and acupuncture applications. In conclusion, both TENS and acupuncture applications seem to be beneficial in FMS patients.

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Objective: This single-blind, randomized study aimed to evaluate effects of acupuncture stimulation at the GV 20 point on the electroencephalogram (EEG). Methods: Data was collected from 17 volunteers, aged 18-25 years old. EEG recordings were obtained before and after verum acupuncture and after a one-week interval EEG recording was also obtained before and after sham acupuncture. Spectral analysis of the EEG data was compared to baseline EEG. Results: Compared to baseline, there was an increase in the alpha band power at the T4 and T5 electrodes (p < 0.05) and a decrease in the beta band power at the T4, T6, and A2 electrodes following verum acupuncture. However, comparison of the data recorded before and after sham acupuncture revealed no significant differences. Conclusions: We claim that verum acupuncture stimulation at the GV 20 point has an effect on brain activity, which might be due to the known "mood modifying, relaxation effect" at that point.

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