Introduction: In the scenario of dermatological diseases. All other cutaneous and subcutaneous diseases accounted for 0.124% of the total. In this sense, several predictors can influence the composition of the microbiome. The composition of the diet modulates the GM balance, influencing the inflammatory response. One of the first dermatoses in which the positive influence of the use of probiotics was perceived was atopic dermatitis bacteria are very important and, when the lesions worsen, an imbalance in the microbiota is detected. In psoriasis, the use of probiotics seems to help by reducing skin inflammation. Objective: To carry out a concise systematic review of the main relationships of the nutrition-gut microbiota-skin axis, highlighting the importance of nutrology and gut microbiota for dermatological health. Methods: The research was carried out from June 2021 to July 2021 and developed based on Scopus, PubMed, Science Direct, Scielo, and Google Scholar, following the Systematic Review-PRISMA rules. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results: It was found that in the context of the interaction of nutritional health, metabolism encompasses the interactions between diet, microbiota, and cellular enzymatic processes that generate the chemical pathways necessary to maintain life. For the understanding of the regulatory processes that involve the nutrition-gut microbiota-skin axis, chronic inflammation is a crucial factor for the development of autoimmune diseases. For example, pathological T cells residing in the skin of patients with psoriasis produce excess IL-17 in response to IL-23, triggering the production of pro-inflammatory mediators IL-1β, IL-6, IL-8, TNF- α, and keratinocyte chemoattractants. The interaction of hormonal, neuronal, and inflammatory signaling has a major impact on skin health. Conclusion: Several studies have scientifically demonstrated the important relationship between GM and adequate nutrition for the establishment of the nutrition-gut microbiota-skin axis, highlighting the management of dermatoses with probiotics and prebiotics, as well as changes in lifestyle.
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