Introduction A cross-sectional study was conducted between the months of April to October 2015, to determine the effects of intestinal parasitic infections (IPIs) on nutritional status of school age children in Owerri and Orlu geographical zones, in Imo State, Nigeria. Methods Faecal samples were examined using Kato Katz method and formol-ether concentration techniques, while blood samples were examined using cyamethahaemoglobin method. Anthropometric indices were used as indicators of nutritional status, children whose Height-for-Age, Weight-for-Age and Weight-for-Height were <-2 standard deviation (SD) were classified as stunted, wasted, and underweight respectively. Results Total prevalence rate of 16.6% was recorded in the study areas with Ascaris lumbricoides (4.0%), Trichuris trichiura (0.6%), Hookworm (1.0%) Taenia sp (0.3%), Entaomeba histolytica (5.3%), Entamoeba coli (2.7%) and Giardia lambia (2.7) Majority (73.4%) of the children had light intensity. Anthropometric study results showed that 79(31.3%) of the children were malnourished. The prevalence of stunting, under-weight and wasting were higher in uninfected (86.1%, 90.0% and 10%) respectively than in infected children (13.9%, 10.0% and 0.0%) respectively, although not significant at p = 0.857, 0.587 and 0.368 respectively. Prevalence of anaemia was 17.4%, anaemia was insignificantly (p = 0.09) higher in infected (21.1%) than in uninfected (16.5%) children. Children that had co-infection recorded higher prevalence (2.2%) of severe anaemia. There was an association (p = 0.002) between anaemia and intensity of helminth infection. Malnutrition was insignificantly (p = 0.319) higher in children with heavy (100.0%) and moderate (75.0%) intensity of helminth infection than children that had light intensity (41.7%) of helminth infection. Conclusion When compared with previous study, there were decline in the prevalence of intestinal parasitic infections and anaemia among school age children. Low intensity parasitemia with intestinal parasites had no significant effect on the malnutrition and haemoglobin profile of the children in the study areas. Therefore, improved sanitation and more deworming efforts should be intensified to ensure further decline in prevalence of intestinal parasitic infections.

In Nigeria infection with onchocerciasis has been under control with the introduction of ivermectin in most affected communities for a decade. To assist ‘stop mass drug administration (MDA)’ decision, a cross-sectional survey evaluated the impact of ivermectin on onchocercal Skin Diseases (manifestations) from 540 participants in 5 endemic communities. The rapid epidemiological assessment (REA) method with palpable nodules and skin depigmentation (leopard skin, LS) as diagnostic indices were used. The prevalence profiles of palpable nodules and leopard skin was 5.9% and 12.2% respectively. Prevalence of clinical features varied among the farming community (P<0.05). Similarly, age group 21-30 years had significant prevalence of clinical features than other age groups (P<0.05).  Males had significantly higher prevalence of these indices (palpable nodules 6.8(%; LS 13.3%) than females (palpable nodules 4.6%; LS 11.1%). Although, Onchocercal Skin Diseases (clinical manifestations) were observed in all age groups, it occurred most in older groups. These groups with nodules could portend as reservoir for transmission. The implications of the results were discussed in the context of the on-going prediction of possible elimination of onchocerciasis in Africa and ‘stop MDA’ decision.