Future energy-efficient aircraft requires a further drastic reduction in drag and weight. Is it contradictory to improve both at the same time? Is it possible to design a highly efficient HLFC system to be weight-neutral? The present study, performed within the Cluster of Excellence SE 2 A -Sustainable and Energy-Efficient Aviation, summarizes aspects and considerations of the contributing disciplines to derive a solution for a suction-based system on short-range aircraft wings with maximum efficiency, i.e. hybrid laminar flow control application capabilities at minimum weight penalty. Several new features -novel wing design and simulation tools, the potentials of thin plies for weigth saving and the 3D-printing possibilities for ventable core structures -are investigated to achive this goal.