RESUMODistúrbios dos hormônios tireoideanos há muitos anos são associados à depressão, no entanto, a natureza dessa relação tem levotiroxina, comparados com controles com função tireoidena normal. Para avaliação da presença de depressão foi usado o Inventário de Depressão de Beck (IDB). Participaram do estudo 40 pacientes. A pontuação no IDB teve média de 16,1 ± 13,2 no grupo hipotireoidismo; e de 9,5 ± 7,2, no grupo controle (p = 0,054). Não houve relação entre níveis séricos maiores de TSH e Palavras-chave: Hipotireoidismo. Depressão. Hormônios tireoideanos. ABSTRACTDisorders of the thyroid hormones have long been associated with depression, however, the nature of this relationship has been sectional study, the presence of depression in patients with primary hypothyroidism properly treated with levothyroxine compared with controls with normal thyroid function. To evaluate the presence of depression was used Beck Depression Inventory (BDI). The study included 40 patients. The score on the BDI averaged 16.1 ± 13.2 in the hypothyroidism group; and 9.5 ± 7.2 in the control group (p = 0.054). There was no relationship between higher serum levels of TSH and higher scores on the BDI. There was although it was observed a tendency to an increased risk of depression in hypothyroidism group. Considering the limited sample