To evaluate time, reliability and accuracy of craniofacial measurements with a 3D light scanner, considering prior demarcation of surface points on the face. Materials and methods: Eleven facial measurements of 15 volunteers were obtained by a scanner (Artec Eva TM) and by a caliper directly on the face, with or without demarcation of facial reference points. Inter and intramethod comparison were examined by intraclass correlation coefficient and analysis of random error by the Dahlberg formula. Agreement between the methods was analyzed by the Bland-Altman. A Wilcoxon test was used to compare the time for each method, at p < 0.05. Results: Marking points on the face improved accuracy for both methods. In the inter-methods analysis with landmarks, the scanner showed excellent reliability in all measures (ICC = 0.92-0.97, p < 0.0001). Measurements accuracy with scanner was around 2 mm when the points were not previously marked and about 1 mm when the points were marked. Measures taken with the scanner, however, took twice as long, compared with the direct method. Conclusions: Craniofacial measurements obtained with scanner showed excellent reliability and accuracy, which qualifies this method for clinical and scientific use. Accuracy is improved when the points were previously marked on face. However, the time needed to obtain measurements is greater than about 4 min for the direct method. 2. Material and methods The study was approved by the Ethics in Research Committee