INTRODUCTION: Individuals with human T-cell lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) experience sensorimotor alterations, which can affect functional performance. Virtual reality (VR) videogaming is a therapeutic option, though there is scarce evidence for its use in this population. We aimed to investigate the therapeutic effects of a VR video game on functional mobility, balance, and gait speed in individuals with HAM/TSP. METHODS: We conducted a blinded, crossover clinical trial comprising 29 individuals with HAM/TSP and randomized them into two groups: (1) early therapy: rehabilitative protocol started immediately after the initial evaluation and (2) late therapy: rehabilitative protocol started 10 weeks later. We assessed all participants for balance using the Berg Balance Scale (BBS) scores, functional mobility using the Timed Up and Go (TUG) test, and gait speed using video camera and CvMob software. Differences were considered significant if p <0.05. RESULTS: The early therapy group individuals presented with higher BBS scores ( p =0.415), less TUG times ( p =0.290), and greater gait speed ( p =0.296) than the late therapy group individuals. CONCLUSIONS: VR videogaming is a useful option for rehabilitative therapy in individuals with HAM/TSP; it positively affects balance, functional mobility, and gait speed.

| Introduction: Systemic lupus erythematosus(SLE) is a chronic autoimmune disease of a diffuse nature, which causes, among other factors, joint involvement Jaccoud arthropathy (AJ) is a reversible deforming inflammation that occurs in the proximal joints, Frequently seen in upper limbs. The epidemiological prevalence of AJ is 5% for SLE patients. Poor alignment or loss of strength can limit movement, generate compensations and joint overloads. Early functional diagnosis may help reduce the installation of joint deformities. Objective: To compare the range of motion and palmar grip strength in people with and without AJ associated with SLE. Methods: A cross-sectional study where patients were allocated to two groups: diagnosed with SLE and diagnosed with SLE associated with AJ. The instruments used: dynamometer, finger goniometer and the universal goniometer. Results: 67 women with SLE participated in the study, of which 32 had AJ. The sociodemographic and clinical characteristics of the groups were considered homogeneous for the analyzed variables. A significant difference was observed between groups, except for the extent of interphalangeal extension of the first right mandibular (p = 0.073), distal interphalangeal of the fourth left (p = 0.083) and distal interphalangeal of the first left mandibular (p = 0.435 ). Conclusion: People with AJ associated with SLE had higher joint amplitude and lower palmar grip strength compared to those with SLE alone. These results suggest that there is still a need for complementary studies to observe the functionality of these people's hands.Key-Words: Systemic Lupus Erythematosus. Jaccoud Arthropathy. Muscular Strength. Goniometry. Deformity in hands RESUMO | Introdução: O lúpus eritematoso sistêmico (LES) é uma doença autoimune, crônica, de caráter difuso, que causa, dentre outros fatores, comprometimento articular A Artropatia de Jaccoud (AJ) é uma inflamação deformante e reversível, que ocorre nas articulações proximais, mais frequentemente observadas em membros superiores. A prevalência epidemiológica da AJ é de 5% para pacientes com LES. O mau alinhamento ou a perda de força podem limitar o movimento, gerar compensações e sobrecargas articulares. O diagnóstico funcional precoce pode auxiliar a reduzir a instalação das deformidades articulares. Objetivo: Comparar a amplitude de movimento e a força de preensão palmar em pessoas com e sem AJ associado LES. Métodos: Estudo transversal onde os pacientes foram alocados em dois grupos: com diagnóstico de LES e com diagnóstico de LES associado à AJ. Os instrumentos utilizados: dinamômetro, goniômetro de dedos e o goniômetro universal. Resultados: Participaram do estudo 67 mulheres com LES, das quais, 32 tinham AJ. As características sociodemográficas e clínicas dos grupos foram consideradas homogêneas para as variáveis analisadas. Foi observada uma diferença significativa entre os grupos, com exceção do grau de extensão da interfalangeana do primeiro quirodáctilo direito (p= 0,073), da interfalangeana distal do quarto q...