Even in the age of big data in Biology, studying the connections between the biological processes and the molecular mechanisms behind them is a challenging task. Systems biology arose as a transversal discipline between biology, chemistry, computer science, mathematics, and physics to facilitate the elucidation of such connections. A scenario, where the application of systems biology constitutes a very powerful tool, is the study of interactions between hosts and pathogens using network approaches. Interactions between pathogenic bacteria and their hosts, both in agricultural and human health contexts are of great interest to researchers worldwide. Large amounts of data have been generated in the last few years within this area of research. However, studies have been relatively limited to simple interactions. This has left great amounts of data that remain to be utilized. Here, we review the main techniques in network analysis and their complementary experimental assays used to investigate bacterial-plant interactions. Other host-pathogen interactions are presented in those cases where few or no examples of plant pathogens exist. Furthermore, we present key results that have been obtained with these techniques and how these can help in the design of new strategies to control bacterial pathogens. The review comprises metabolic simulation, protein-protein interactions, regulatory control of gene expression, host-pathogen modeling, and genome evolution in bacteria. The aim of this review is to offer scientists working on plant-pathogen interactions basic concepts around network biology, as well as an array of techniques that will be useful for a better and more complete interpretation of their data.

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el presente artículo se ocupa de analizar los Programas de estudio de educación para la afectividad y sexualidad integral del Ministerio de Educación Pública de Costa Rica (MEP). Para ello realiza una contextualización, en primer lugar, histórico-normativa y, en segundo lugar, política de dicha directriz educativa. Asimismo, el texto se interesa en estudiar el modo en que distintas agendas condicionan y tensan los contenidos de los Programas. Específicamente, el artículo se adentra en las concepciones del cuerpo, el género y el deseo de los Programas... para mostrar las visiones enfrentadas que implícitamente estructuran tales concepciones. El objetivo, así, es discutir críticamente la Educación Sexual en general, y los Programas de estudio de educación para la afectividad y sexualidad integral en particular, más allá de las posiciones dicotómicas (a favor-en contra) que suelen emplearse para tales efectos.

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