SummaryA young woman whose serum was positive for hepatitisassociated antigen (HA.A.) and alpha-fetoprotein developed a malignant hepatoma. Though the lightmicroscopical appearances of the surrounding liver tissue were normal, electronmicroscope examination of the tumour tissue disclosed both C-virus-like particles and ILA.A. particles. Possibly there was a causal connexion between one of these particles and the hepatoma.
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