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Açaí (E. oleracea) and juçara (E. edulis) are berries considered a source of bioactive compounds, especially anthocyanins and unsaturated fatty acids, with recognized health-promoting activities. An integrative review was conducted to identify available clinical trials that evaluated the effects of açaí and juçara intake on the human organism. Science Direct and Medline databases were searched. Human studies that evaluated any biological activities after açaí and juçara intake were included in this review. Twenty-three clinical trials were identified up to April 12, 2020. Studies evaluated the biological effects of açaí (n = 17), juçara (n = 5), or both berries simultaneously (n = 1). The results of these trials suggest both types of berries may contribute to improved antioxidant defense and to attenuating metabolic stress and inflammation. However, considerable heterogeneity was observed among trials, and few studies explored the bioactive compounds of the food matrix provided in the interventions. More clinical trials are encouraged to strengthen the current evidence on human biological outcomes, including comparative analysis between these berries.

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