In this study, it was aimed to synthesize and characterize a new polymeric cryogel system to be formed with polymeric linoleic acid (PLina), a vegetable oil-based polymeric fatty acid, and the widely preferred 2-hydroxyethyl methacrylate (HEMA) monomer. cryogels. For this purpose, firstly, autoxidation and hydroxylation reactions were carried out for polymeric lineloic acid, respectively. Hydroxylated polymeric lineloic acid (PLina-OH) and HEMA monomer were subjected to a cryogenic gelation reaction in the presence of N,N′-methylene bisacrylamide (MBAA) as crosslinking agent. The obtained new cryogel was characterized by FTIR, SEM, BET, TGA analyses. The swelling behavior of the synthesized PLinaOH-HEMA cryogels in water was concluded with kinetic studies. In the other hands, some of polar and non-polar other solvents was used for investigation of all cryogels to see their potentials for solvent uptake.