The novel coronavirus (2019-nCoV) is spreading very fast in Hubei Province of China. As of February 14, 2020, 51,986 confirmed cases (including laboratory-confirmed cases and clinically-confirmed cases) were reported in Hubei Province, and 1,318 of them died. Respiratory droplets and contact transmission are considered to be the most important routes of transmission of 2019-nCoV, but do not fully account for the occurrence of all coronavirus disease 2019 (COVID-19) cases, previously known as novel coronavirus pneumonia (NCP), and the reasons for the rapid spread of this virus (1).In Biosafety Level 3 (BSL-3) Laboratory of the National Institute for Viral Disease Control and Prevention, Vero cells were used for viral isolation from stool samples of COVID-19 patients sent by Heilongjiang CDC. A 2019-nCoV strain was isolated from a stool specimen of a laboratory-confirmed COVID-19 severe pneumonia case, who experienced onset on January 16, 2020 and was sampled on February 1, 2020. The interval between sampling and onset was 15 days. The full-length genome sequence indicated that the virus had high-nucleotide similarity (99.98%) to that of the first isolated novel coronavirus isolated from Wuhan, China (Figure 1). In the Vero cells, viral particles with typical morphology of a

The unstable triplet excited state is a core problem when developing selfprotective room temperature phosphorescence (RTP) in carbon dots (CDs). Here, fluorine and nitrogen codoped carbon dots (FNCDs) with long-lived triplet excited states, emitting pH-stabilized blue fluorescence and pHresponsive green self-protective RTP, are reported for the first time. The self-protective RTP of FNCDs arises from n-π * electron transitions for CN/CN bonds with a small energy gap between singlet and triplet states at room temperature. Moreover, the interdot/intradot hydrogen bonds and steric protection of CF bonds reduce quenching of RTP by oxygen at room temperature. The RTP emission of FNCDs shows outstanding reversibility, while the blue fluorescence emission has good pH stability. Based on these FNCDs, a data encoding/reading strategy for advanced anticounterfeiting is proposed via time-resolved luminescence imaging techniques, as well as steganography of complex patterns.

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