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Introduction:The occurrence of mental disorders and chronic diseases is associated with low treatment compliance and an increased mortality. The main objective of this study was to analyze medication prescriptions at hospital discharge in order to verify the patients' access to the prescribed treatment.Methods: This is a descriptive and retrospective study performed between September 2013 and September 2018 with patients admitted in the psychiatric ward of a university hospital in the state of Rio Grande do Sul. The studied patients consisted of 274 adults over 18 years of age admitted to this hospital with at least one psychiatric comorbidity included in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) who lived in the city of Porto Alegre used specially controlled drugs, and had been hospitalized for at least 7 days.Results: Out of the 274 patients, 68.5% were readmitted once, 17.5% were readmitted twice, 9.5% were readmitted 3times, and 4.5% went through this process 4 times or more. A significant association (p = 0.014) was observed between the number of drugs not included in the Municipal Essential Medicines List upon first readmission and the number of readmissions. Among patients who were readmitted 3 times or more, 79% were prescribed drugs that were not on this list. Conclusions:The understanding of how therapeutic itineraries are established when searching for drugs contributes to setting effective lines of care where professionals may position themselves more proactively to reduce mental health complications.

Este artigo objetivou estabelecer o perfil dos usuários com diabetes insulinizados e fatores associados ao autocuidado na sua terapêutica. Trata-se de um estudo quantitativo, descritivo, transversal, com amostra de 139 pessoas atendidas na Farmácia Municipal de São Leopoldo - RS. Utilizou-se a versão brasileira adaptada do "Questionário de Atividades de Autocuidado com o Diabetes”. Foram incluídas perguntas para avaliar o perfil sociodemográfico desses pacientes. O perfil dos usuários investigados foi: população idosa na faixa de 61 a 70 anos (29,5%), feminina (58,3%), com diabetes mellitus tipo 2 (64,0%), aposentados (39,6%) e com nível de escolaridade até o ensino médio incompleto (52,5%). Nas atividades de autocuidado, a menor adesão foi a realização de atividade física, dieta saudável e monitorização da glicemia capilar. A maior aderência foi no uso de insulina (média 6,56 ± 1,26). Conhecer o perfil dos usuários com diabetes insulinizados pode contribuir com o fortalecimento do autocuidado e contribuir na qualidade de vida destes pacientes.

BackgroundThe potential drug-drug interactions (PDDI) in a multidrug treatment (MDT) regimen must be taken into account when prescribing, as adverse effects (AEs) may occur that might make it necessary to choose an alternative treatment.MDT regimens are usually being prescribed by different doctors. This practice increases the risk of DDI and it is fundamental to acknowledge them and identify at-risk patients early.The AEs resulting from DDI can be reduced or avoided with dose adjustments or changes in the regimen, or even stopping some drugs.DDIs can be classified according to severity as major, moderate and minor. The focus of our study was in the group of potential major drug–drug interactions (PMDDI), which can threaten the patient’s life or result in permanent injury.PurposeTo analyse the PDDI profile of medical prescriptions according to severity and identify the most frequent PMDDI and the drugs involved.Material and methodsRetrospective study of PDDIs (checked on Drug Interactions Checker of drugs.com) on all prescriptions of medical ward patients, who were discharged from February to March 2014, by consulting the patient’s clinical record. Descriptive statistical analysis was performed.The following data were collected: number of prescriptions/patient analysed, patients’ average age, average number of prescribed drugs/prescription, maximum number of major interactions/prescription,% of prescriptions with interactions detected; % of prescriptions with potential major interactions (MI), main drugs involved (MD) and more frequent interactions (MFIs).ResultsAbstract PS-077 Table 1Prescriptions/patient analysed234Average age75.3 ± 15.2 years (132?, 102?)Prescribed drugs/prescription11.5 ± 4.5Major interactions/prescription11% of prescriptions with interactions detected97.50% % of prescriptions with potential major interactions71.4% Main drugs involvedEnoxaparin (10.9%)/Potassium Chloride (9%)More frequent interactionsAcetylsalicylic Acid-Enoxaparin (11.1%)ConclusionThe data analysis revealed a huge number of PDDI. This leads us to the conclusion that the pharmacist intervention in this area will increase safety in medicines administration.In future the development of an intervention plan regarding the most frequent PMDDIs will improve the health care provision.It’s our goal to introduce an automatic notification system for the prescriber at the time of prescription in order to manage these interactions.References and/or acknowledgementsNo conflict of interest.

Introduction: Renal Failure is a pathology that affects about 10% of the world population, which has the possibility of treatment, in the most serious cases, renal replacement therapy (RRT). The main evidence of care in the Intensive Care Unit is fundamental for safe and effective performance Methodology: integrative review formulated through research in original articles using the PICO method, the research took place from May to July 2021 using the following descriptors: Renal Failure, Care of Nursing and Intensive Care Unit in the following databases: Latin American and Caribbean Literature on Health Sciences Information (LILACS), Virtual Health Library (BVS), Scientific Electronic Library Online (SciELO) and BDENF respecting the limits for publication between 2016 and 2021. Results: Nursing actions are guidelines regarding food balance and fluid intake, management of intradialytic complications and their prevention, such as monitoring signs of acceleration, administration of anticoagulants, antiemetics, saline solution acid-base control and access route maintenance. Conclusion: The use of care protocols and in this environment streamlines the work of the professional nurse in managing the intradialytic occurrence, continuing education and offering training are essential for adequate care.