Individual's senescence process takes place slowly and continuously beyond generates several changes including skin aging, since the decline in cellular activities. Countless resources have been created over the years, with the goal of stopping and / or reversing the unsightly aspects of the skin caused by this process. Thus, plasma jet, a new therapeutic resource has been used in order to promote rejuvenation through the reduction of wrinkles and expression lines. Objective: To evaluate the pattern of thermal variation of the tissue treated with a plasma jet, using infrared thermography. Methodology: This was a series of clinical cases involving 5 female patients over the age of 40 who had facial wrinkles. Patients were previously evaluated and anesthetized. Then, plasma jet therapy was performed in the supra-orbital region. Patients were evaluated for thermal imaging before and after anesthesia and post-therapy. Result: It was found through thermographic analysis, a significant variation in the temperature coefficient of the skin where the anesthetic was applied and then the plasma jet (ΔT > 0.4 °C). Conclusion: The present study proved through the use of thermography that the plasma jet was able to generate an increase in local temperature. The authors suggest that such thermal variation may be the result of a process of vasodilation in the treated region.

Background: The unaesthetic appearance of the female intimate area (vulva, "mound of venus" and perianal region) is a triggering factor of negative psychological responses, embarrassment, anxiety and insecurity in many women. Using rejuvenating equipment for vaginal structure or for the intimate area as a whole is already widespread in the literature, and High-Intensity Focused Ultrasound (HIFU) has proven to be very effective in the clinical practice of many professionals. This study, therefore, aims to describe the fundamentals and applicability that guide the use of HIFU in vulvar rejuvenation. Materials and Methods: Exploratory research was carried out, presented in a narrative review, to highlight the action of HIFU in female intimate rejuvenation. The review explored scientific articles published and available in the following databases: MEDLINE (Medical Literature Analysis and Retrieval System Online), PubMed (National Library of Medicine), SCIELO (Scientific Electronic Library Online), and LILACS (Latin Literature American and the Caribbean in Health Sciences). In addition, some clinical findings obtained through a retrospective analysis of medical records were added to describe the authors' clinical experience in the use of Focused Ultrasound (HIFU) for vulvar rejuvenation. Results: We verified that the tissues of female external genitalia respond very well to the stimuli of the focused sound waves of the HIFU, being able to produce immediate and lasting results through isolated applications or in association with intradermotherapy or other therapeutic resources. Conclusion: We conclude that using High Intensity Focused Ultrasound

Laser photobiomodulation and ozone therapy are therapeutic possibilities for antimicrobial control and biomodulation of tissue repair. This study aimed to compare the effect of laser photobiomodulation with that of ozone gas in wound healing of experimental lesions on animal's tissues. It was a systematic literature review, which aimed to search for articles of the animal model experimental study according the PRISMA guidelines. The search was made through the electronic articles indexed in the databases: PubMed, BVSalud, Cochrane, Scielo and Google Scholar, based on the DeCS/MeSH descriptors in English and Portuguese. The sample included studies from 2013 to 2020 and methodological quality was assessed using the ARRIVE guideline. A total of 329 of records indentified through database searching. Five studies were selected for the present systematic review according to the inclusion and exclusion criteria outlined for the research. All studies performed histological analysis of the treated tissue sections. Ozone therapy and laser showed a significant difference in favor of repair in different tissues when compared to the findings of the control groups in all studies. When compared to each other, ozone showed superiority over laser in two of the five studies, in addition to two studies having similar results between these two therapies. Regarding the ARRIVE guideline, in the most studies, the meeting criteria was high, with good methodological quality. Most studies highlighted the lack of uniformity in the therapy protocol as the greatest difficulty encountered, although they were unanimous in stating that laser photobiomodulation and ozone therapy contributed to the improvement of the healing pattern.

Tissue repair process consists in a complex and dynamic event straightly linked to tissues self-regeneration capability. In that context, it may also occur total or partial replacement of the original tissues through an extracellular matrix with significant collagen and elastin expression that results in fibroplasia. Aiming to optimizing the repair, it has been used some resources able to biomodulate the action of different kinds of tissue cells such as laser photobiomodulation (LP), light emitting diodes (LEDs), ozone therapy and plasma jet. This narrative literature review aims to describe the different phases of tissue repair and discuss about biomodulator therapies commonly applied to stimulate that process. Manuscripts discussing the proposal theme, which have been fully available were selected from Pubmed, Embase, Cochrane and Scielo database. The manuscripts must be written in English or Portuguese language, according to the exclusion and inclusion criteria designed for that study. Sixty manuscripts were selected. It may be noticed that biomodulator therapies have been used in health areas. However, studies evaluating the influence of plasma jet on tissue repair are still scarce. Preliminary results from such studies suggest that plasma jet therapy may perform important antiinflammatory, analgesic and biostimulating effects.