HIV/syphilis co-infection is common because both conditions affect similar risk
groups. HIV interferes with the natural history of syphilis, which often has atypical
clinical features and nervous system involvement in the early stage of disease. We
report the case of an HIV-positive patient with secondary syphilis, scaling
palmoplantar keratoderma, scrotal eczema, balanitis and urethritis mimicking Reiter’s
syndrome. Immunohistochemistry using polyclonal antibodies against Treponema pallidum
revealed the presence of spirochetes, associated with the paretic form of parenchymal
neurosyphilis. The patient was given crystalline penicillin, with complete resolution
of dermatological and neurological symptoms, and no sequelae.
Sebaceous adenocarcinoma is a rare adnexal tumor that can affect the skin and is
divided into ocular, a more common form and extra ocular, of a rarer occurrence. We
report the case of a patient diagnosed with Acquired Immune Deficiency Syndrome
(AIDS) who developed an extra ocular, bulky and fast-growing sebaceous adenocarcinoma
on the face. The literature has suggested that transplanted patients and HIV-positive
patients have an excess risk for developing adnexal tumors, including sebaceous
adenocarcinoma.
Synovial sarcomas are rare malignant tumors affecting mainly young adults, presenting
as a slow growth mass located in deep soft tissues of extremities, near the joints.
In this report a 34-year-old male patient, presented an ulcerovegetative lesion on
the right wrist which was completely excised. Histopathology and immunohistochemistry
confirmed synovial sarcomas with poorly differentiated cells. This patient presented
11 months later with ipsilateral axillary lymph node metastasis, which emphasizes the
unfavorable prognosis of this synovial sarcoma variant. The indolent growth pattern
of this sarcoma justifies the well circumscribed initial stages, which progressively
infiltrate adjacent structures with lung metastasis (80%) and lymph node involvement
(20%) and thus corroborates the importance of early diagnosis and proper
treatment.
Dermoid cysts or mature cystic teratomas are mesenchymal neoplasms most commonly found in the ovaries, but which may occur in any location along the pathways of ectodermal cell migration. They are rarely seen in the pancreas, where they show a slight preference for the pancreatic head. We report a case of dermoid cyst of the pancreas in a 69-year-old male patient, discussing the epidemiology, clinical presentation, diagnosis and treatment of this neoplasm. Since preoperative diagnosis is difficult, given its rarity in this site, it is usually diagnosed by histopathology of the specimen.
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