Ranibizumab was an effective treatment for stabilising and improving vision with a low number of injections in 92.5% of patients with myopic CNV in a long-term follow-up.

Myopic CNV equally benefits from on-demand intravitreal injection of either bevacizumab or ranibizumab; the therapeutic effect is independent of previous PDT and age.

Ranibizumab can be considered as an effective therapy in angioid streak-related neovascularization, even if in an off-label setting.

The European Union (EU) and the United Nations (UN) are expressions of a rules-based global order. The EU has enshrined support to the UN in its security strategies, and its priorities indicate an engagement in a wide range of UN programs and activities to maintain the rules-based order and adapt it to face internal and external challenges. The EU and its member states are the largest contributors to the UN budget. Following the adoption of the Lisbon treaty, the EU has increased its representation at the UN, gaining enhanced observer status in the General Assembly. However, because of the intergovernmental nature of the forum, only its member states have the right to vote. This has led scholars to investigate the actorness of the EU at the UN through the analysis of the voting cohesion of EU member states in the General Assembly. Less attention has been paid to the behavior of EU member states in the Security Council. Existing scholarship has tended to analyze how the EU acts within the UN more than inter-organizational cooperation. However, the contribution of the EU and its member states to UN activities in the area of peace and security maintenance is particularly relevant and is a reminder that inter-organizational cooperation deserve greater attention than the one it has received so far.

Political coalitions in the international system are still understudied in International Relations theory. This article claims that the formation of and variations in coalitions in the international system are affected by changes in their bargaining power and bargaining environment related to the global leadership cycle and by long-term organisational changes of the international political system. Identifying the Security Council as the institution in which states are more likely to keep their systemic preferences at the institutional level, the article studies the presence, formation and change of coalitions in the international system by testing variations in the behaviour of the Security Council members in the period 1993–2012. To overcome methodological difficulties, it proposes to analyse sponsoring rather than voting behaviour. In the analysed period, the presence of a mutating dominant coalition, signs of potential coalitions in the making and an increase in participation and competition resulting from modifications in the organisational form of the international system are found