Background: The COVID-19 pandemic rapidly strained healthcare systems worldwide. The reference standard for diagnosis is a positive reverse transcription polymerase chain reaction (RT-PCR) test, but results are not immediate and sensibility is variable. Aim: To evaluate the diagnostic accuracy of lung ultrasound compared to chest X-ray for COVID-19 pneumonia. Design and Setting: A retrospective analysis of symptomatic patients admitted into one primary care centre in Spain between March and September 2020. Method: Patients’ chest X-rays and lung ultrasounds were categorized as normal or pathologic. RT-PCR confirmed COVID-19 infection. Pathologic lung ultrasound images were further categorized as showing either local or diffuse interstitial disease. McNemar and Fisher tests were used to compare diagnostic accuracy. Results: Most of the 212 patients presented fever at admission, either as a standalone symptom (37.74% of patients) or together with others (72.17% of patients). The positive predictive value of the lung ultrasound was 90% for the diffuse interstitial pattern and 46.92% for local pattern. The lung ultrasound had a significantly higher sensitivity (82.75%) (p < 0.001), but lower specificity (71%) than the chest X-ray (54.02% and 86%, respectively) (p = 0.008) for identifying interstitial lung disease. Moreover, sensitivity of the lung ultrasound for severe interstitial disease was 100%, and was significantly higher than the chest X-ray (58.33%) (p = 0.002). Conclusion: The lung ultrasound is more accurate than the chest X-ray for identifying patients with COVID-19 pneumonia and it is especially useful for those presenting diffuse interstitial disease.
Human-caused wildfires are often regarded as unpredictable, but usually occur in patterns aggregated over space and time. We analysed the spatio-temporal configuration of 7790 anthropogenic wildfires (2007)(2008)(2009)(2010)(2011)(2012)(2013) in nine study areas distributed throughout Peninsular Spain by using the Ripley's K-function. We also related these aggregation patterns to weather, population density, and landscape structure descriptors of each study area. Our results provide statistical evidence for spatio-temporal structures around a maximum of 4 km and six months. These aggregations lose strength when the spatial and temporal distances increase. At short time lags after a wildfire (<1 month), the probability of another fire occurrence is high at any distance in the range of 0-16 km. When considering larger time lags (up to two years), the probability of fire occurrence is high only at short distances (>3 km). These aggregated patterns vary depending on location in Spain. Wildfires seem to aggregate within fewer days (heat waves) in warm and dry Mediterranean regions than in milder Atlantic areas (bimodal fire season). Wildfires aggregate spatially over shorter distances in diverse, fragmented landscapes with many small and complex patches. Urban interfaces seem to spatially concentrate fire occurrence, while wildland-agriculture interfaces correlate with larger aggregates.
Our understanding of the environment, its connections to biodiversity, health and well being as well as how it is changing are informed by data. The mechanisms and procedures generating those data are continually evolving, which means that the complexity of environmental systems can be studied in greater depth, and hidden connections discovered. Statistical methods also need to evolve to deal with these new data streams. It is in this landscape, that we often see mention of the digital environment agenda, or sometimes digital twin, and more recently digital earth initiatives. These terms all capture the concept that we are studying a temporally evolving system over space, and that monitoring and measurement are essential. Using examples of freshwater quality and biodiversity connectivity, I will illustrate some of the challenges and potential solutions to statistical thinking about a digital earth.
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