The solid-state fermentation (SSF) has been employed as a form making available a higher content of functional compounds from agroindustrial wastes. In this work, the effect of SSF with the Rhizopus oryzae fungus on the phenolic acid content of rice bran was studied. Phenolic extracts derived from rice bran and fermented rice bran were evaluated for their ability to reduce free radical 1,1-diphenyl-2-picrihidrazil (DPPH) and for the ability to inhibit the enzymes peroxidase and polyphenol oxidase. The phenolic compound content increased by more than two times with fermentation. A change in the content of phenolic acids was observed, with ferulic acid presenting the greatest increase with the fermentation, starting from 33μg/g in rice bran and reaching 765μg/g in the fermented bran. [corrected]. The phenolic extracts showed an inhibition potential for DPPH and for the peroxidase enzyme, however did not inhibit the polyphenol oxidase enzyme.
Background and objectives
The Covid-19 pandemic has put healthcare professionals around the world in an unprecedented challenge. This may cause some emotional difficulties and mental health problems. The aim of the present study was to analyze the emotional status among the health care workers form the Hospital of Igualada (Barcelona), while they were facing with Covid-19 in one of the most affected regions in all of Europe.
Patients and methods
A total of 395 participants were included in the study. A cross-sectional assessment was carried out between the months of March and April. Information about anxiety, depression, and stress was gathered. We also collected demographic data and concerning potentially stressful factors.
Results
A significant proportion of professionals reported symptoms of anxiety (31.4%) and depression (12.2%) from moderate to severe intensity. Symptoms of acute stress were reported by 14.5% of participants. We performed a regression analysis, which explained the 30% of the variance associated with the degree of emotional distress (R² = 0.30). The final model reveals that females (or young males), who are working in the frontline as nursing assistants, caretakers or radiology technicians, with the uncertainty of a possible infection, the perception of inadequate protection measures and having experienced the death of a close person by Covid-19, showed a heightened risk of experiencing psychological distress.
Conclusions
Coping with the Covid-19 pandemic caused a significant impact on emotional status of healthcare workers involved in this study.
OBJECTIVE: To translate into Brazilian Portuguese the Autism Diagnostic Interview-Revised (ADI-R), an extremely useful diagnostic tool in autism. METHODS: A case-control study was done to validate the ADI-R. After being translated, the interview was applied in a sample of 20 patients with autism and 20 patients with intellectual disability without autism, in order to obtain the initial psychometric properties. RESULTS: The internal consistency was high, with a of Crombach of 0.967. The validity of criterion had sensitivity and specificity of 100%, having as a gold standard the DSM-IV diagnostic criteria. The interview had high discriminant validity, with higher scores in the group of patients with autism, as well as high interobserver consistency, with median kappa of 0.824. CONCLUSION: The final version of ADI-R had satisfactory psychometric characteristics, indicating good preliminary validation properties. The instrument needs to be applied in bigger samples in other areas of the country.
ResumoA legislação brasileira determina que todas as crianças devem ter acesso à escola comum, incluindo sujeitos com transtornos do espectro do autismo (TEA). Embora um corpo substancial de pesquisas descreva os benefícios derivados da inclusão dessas pessoas, o tema ainda permanece controverso, principalmente quanto à possibilidade das escolas oferecerem respostas adequadas às necessidades de crianças com TEA. O presente artigo tem por objetivo identificar o que as produções científicas nacionais, publicadas entre 2008 e 2013, têm revelado sobre a inclusão de pessoas com TEA no Brasil. Os resultados mostram que a presença desses educandos, em escolas regulares, aumentou de forma expressiva após a popularização do paradigma da inclusão. Por outro lado, observa-se que o desconhecimento sobre a síndrome e a carência de estratégias pedagógicas específicas pode acarretar poucos efeitos na aprendizagem desta população.Palavras-chave: Transtorno do Espectro do Autismo; Inclusão; Revisão descritiva.
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