The production of sludge in biological wastewater treatments is a growing problem worldwide as it entails economic, environmental, and health problems. The oxic‐settling‐anaerobic (OSA) process is one of the techniques that have been developed to reduce the sludge produced in the activated sludge process (ASP). This article reports the feasibility of the application of the OSA process in a nutrient removal system, specifically, in an anoxic–oxic (A) process. The results reveal TN removal in the A + OSA system of 68.84% and 69.91% (for 7 and 11 h of sludge anaerobic exposure time, SAET, respectively) versus 38.02% and 32.47% in the OSA system with similar SAET. The percentage sludge reductions obtained were, respectively, 22.41% and 31.93% in the OSA system and 23.53% and 32.49% in the A + OSA system compared to the sludge produced in the conventional ASP. The study confirms the suitability of the application of the OSA process in a nutrient removal system, as nutrient removal performances are not affected, while at the same time achieving higher sludge reduction. © 2017 American Institute of Chemical Engineers Environ Prog, 37: 1068–1074, 2018