BACKGROUNDCutaneous melanoma is a highly aggressive malignancy with increasing incidence
worldwide. The southern Brazilian state of Santa Catarina has one of the highest
incidence rates of melanoma in the country.OBJECTIVETo evaluate the epidemiological profile of melanoma patients in a southern city of
Brazil.METHODSa cross-sectional retrospective study was conducted, aiming to detect the clinical
and histopathological characteristics of cutaneous melanoma diagnosed in the city
of Brusque - SC, between 1999 and 2013.RESULTSA total of 213 cases in 212 individuals were studied. More than 50% of the
patients were females (p< 0.05). The trunk was the most commonly affected site
(p< 0.05), followed by the upper limbs. Nodular and superficial spreading
melanomas were the most commonly detected in histological analyses. They did not
differ statistically in frequency, but were more prevalent than other
histopathological subtypes (p< 0.05). There was no statistically significant
difference between invasive and noninvasive melanomas (p= 0.2441). Among the
invasive melanomas, those with Breslow thicknesses < 1 mm and between 1-2mm
were more prevalent (p< 0.05).CONCLUSIONSIn this study we found a higher frequency of melanomas in female patients and
patients aged over 51. The trunk was the most commonly affected site. Nodular and
superficial spreading melanomas prevailed. Among invasive melanomas, those with
Breslow thicknesses < 2 mm were the most frequent. This paper highlights the
epidemiological profile of melanoma patients in the city and may help to identify
and aid in the follow-up of those who are most likely to present the disease.
Background:The incidence of cutaneous melanoma has increased over the last decades.
Recurrences occur most frequently within the first 2-3 years after diagnosis
but patients carry a lifelong risk of relapse. Nevertheless, there is no
consensus in the literature on what screening tests patients should
undergo.Objectives:To evaluate the most common melanoma metastasis sites among a South Brazilian
population from a city with one of the highest melanoma rates, and establish
the best screening method for these patients.Methods:A cross-sectional retrospective study of 108 consecutive melanoma patients
followed up at a center from 2009 to 2013. Data were collected on
demographic and tumoral characteristics, as well as the site of the first
diagnosed metastasis.Results:Patients were divided into 3 groups for analytical purposes: Non-visceral
metastases (48% of patients), visceral metastasis (39%) and brain metastasis
(13%). We tried to correlate age, gender, mean Breslow thickness, mitosis
and death rates with the aforementioned groups but none showed any
statistically significant association.Conclusion:Melanoma patients must be monitored to detect early relapse and subsequent
effective treatment but the best follow-up strategy remains to be
established.
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