Objective: To identify the overall survival and prognostic factors of malignant lymphoma of the oral cavity and the maxillofacial region. Study Design: Clinical records data were obtained in order to determine overall survival at 2 and 5 years, the individual survival percentage of each possible prognostic factor with the actuarial technique, and the survival regarding the possible prognostic factors with the actuarial technique and the Log-rank and Cox’s regression tests. Results: Of 151 subjects, an overall survival was 60% at 2 years, and 45% at 5 years. The multivariate analysis demonstrated statistically significant differences for clinical stage (p=0.002), extranodal involvement (p=0.030), presence of human immunodeficiency virus (p=0.032), and presence of Epstein-Barr virus (p=0.010). Conclusion: The advanced clinical stage and the larger number of involved extranodular sites are related to a lower overall survival, as well as, the presence of previous infections such as the human immunodeficiency and the Epstein-Barr virus. Key words:Lymphoma, oral cavity, survival.

The results revealed the importance of clinical stage regarding the survival of patients with a primary diagnosis of MC of the salivary glands.

The purpose of this study was to determine the survival and prognostic factors of patients with diffuse large B-cell lymphoma (DL-BCL) of the oral cavity and maxillofacial region. Retrospectively, the clinical records of patients with a primary diagnosis of DLBCL of the oral cavity and maxillofacial region treated at the A.C. Camargo Hospital for Cancer, São Paulo, Brazil, between January 1980 and December 2005 were evaluated to determine (A) overall survival (OS) at 2 and 5 years and the individual survival percentage for each possible prognostic factor by means of the actuarial technique (also known as mortality tables), and the Kaplan Meier product limit method (which provided the survival value curves for each possible prognostic factor); (B) prognostic factors subject to univariate evaluation with the log-rank test (also known as Mantel-Cox), and multivariate analysis with Cox's regression model (all the variables together). The data were considered significant at p ≤ 0.05. From 1980 to 2005, 3513 new cases of lymphomas were treated, of which 151 (4.3%) occurred in the oral cavity and maxillofacial region. Of these 151 lesions, 48 were diffuse large B-cell lymphoma, with 64% for OS at 2 years and 45% for OS at 5 years. Of the variables studied as possible prognostic factors, multivariate analysis found the following variables have statistically significant values: age (p = 0.042), clinical stage (p = 0.007) and performance status (p = 0.031). These data suggest that patients have a higher risk of mortality if they are older, at a later clinical stage, and have a higher performance status.

No abstract

Objectives: To determine predictive indicators for dental health management of patients with different abilities, according to a new screening protocol. Materials and methods:This was an observational, analytical, retrospective, cross-sectional study. The sample consisted of all patients with different abilities, diagnosed with autism, Down syndrome, cognitive deficit, cerebral palsy and others, who received care between 1999 and 2019 at the Oral Health Service of the Centro Ann Sullivan del Peru and met the inclusion criteria. Data were obtained from the clinical histories to determine the predictive indicators for managing dental care in these patients. A multivariate statistical analysis was performed using binary logistic regression test. The research project was evaluated by the Research Project Reviewing Committee and then referred to the Human Ethics Committee from a university, securing the relevant approvals.Results: Of the 589 cases evaluated, mean age was 14.5 years, 67.9% were male; systemic diagnosis of different abilities was autism in 62%, the most frequent treatment was caries (52.1%); and final management of these patients was conscious in 96.4% of the cases. With regard to type of classification and horizon, 67.1% of the cases corresponded to classification A, with 35.9% of these in horizon I. With regard to diagnosis of different abilities, autism presented 40.2% of the cases in classification A and horizon I. A predictive equation of 97.1% probability of whether or not sedation was used was obtained. Regression analysis showed that this model has high sensitivity (100%) and low specificity (15%).Conclusions: Findings show that the type of management for dental care was conscious in nearly all the cases dealt with. This was significantly influenced by the Classification and Horizon Screening Protocol indicator, which established the best predictive model for whether or not to use sedation. The model adequately classifies patients who do not require sedation.