HF remains a condition associated with high mortality and high hospital readmission rates. At the end of the first year, 44.5% of these patients had not needed to visit the ER or had died, which indicates that we should provide HF patients with the best possible care in an attempt to change the natural course of this increasingly frequent syndrome.
BackgroundHeart failure (HF) is a syndrome, whose advanced forms have a poor prognosis,
which is aggravated by the presence of comorbidities.ObjectiveWe assessed the impact of infection in patients with decompensated HF
admitted to a tertiary university-affiliated hospital in the city of
São Paulo.MethodsThis study assessed 260 patients consecutively admitted to our unit because
of decompensated HF. The presence of infection and other morbidities was
assessed, as were in-hospital mortality and outcome after discharge. The
chance of death was estimated by univariate logistic regression analysis of
the variables studied. The significance level adopted was P < 0.05.ResultsOf the patients studied, 54.2% were of the male sex, and the mean age
± SD was 66.1 ± 12.7 years. During hospitalization, 119
patients (45.8%) had infection: 88 (33.8%) being diagnosed with pulmonary
infection and 39 patients (15.0%), with urinary infection. During
hospitalization, 56 patients (21.5%) died, and, after discharge, 36 patients
(17.6%). During hospitalization, 26.9% of the patients with infection died
vs 17% of those without infection (p = 0.05). However, after discharge,
mortality was lower in the group that had infection: 11.5% vs 22.2% (p =
0.046).ConclusionsInfection is a frequent morbidity among patients with HF admitted for
compensation of the condition, and those with infection show higher
in-hospital mortality. However, those patients who initially had infection
and survived had a better outcome after discharge.
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