Postoperative delirium. A window to quality improvement and safety in the care of surgical patients Postoperative delirium or acute confusional state is a common complication among older subjects. Many factors infl uence its appearance, such as preexistent problems of the patient, medication use, pain, the perioperative anesthetic management and the intensity of the infl ammatory reaction to surgical trauma. Its consequences are a longer hospital stay, higher risk of complications and a long term derangement of functional status and cognitive performance. The management of delirium is multifactorial, including the avoidance of precipitating factors, the maintenance of an adequate environment and the conscious use of neuroleptics. The prevention of delirium should be a priority that will improve health care standards.
Background: Development of percutaneous techniques for tracheostomy have facilitated its implementation in the intensive care unit (ICU (Rev Méd Chile 2008; 136: 1113-20).
Endothelium is the inner layer of vessels that separates circulating blood from the rest of the
body tissues. Since its discovery, it has been involved in various functions, both systemic and
organ specific. Currently, endothelial damage and failure in its functions is considered a key
element in pathophysiology of various clinical scenarios, among which we may find COVID-19.
Hence, it has been a target in development of strategies that seek to maintain, enhance or
repair its function. The purpose of the following review is to describe what an endothelial
function is about, its relation with current medical practice, and its implications in the SARSCoV-2 pandemic.
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