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Introduction: Latino grandparents are often involved in rearing grandchildren, but their roles in promoting children's physical activity (PA) have been largely overlooked. This study examined the impact of a community-based intervention called Nietos Activos y Saludables (Active and Healthy Grandchildren) on Latino grandparents' knowledge about and self-efficacy in supporting grandchildren's (aged 2-12 years) PA. Method: The Spanish language intervention, consisting of 4 weekly sessions, was delivered to 12 Latino grandparents (primarily female, aged Ͼ60 years) in Los Angeles County from October to November 2017. Pre-and posttest surveys and postintervention focus groups assessed the intervention impact. Results: Participants indicated that the intervention provided useful information. After intervention sessions, participants achieved a higher score in test on PA requirements for children. They also reported greater knowledge about children's PA, local resources for children's PA, and modifying children's behavior. Additionally, participants reported greater confidence in motivating children in PA and collaborating with parents in promoting children's PA. Results of focus groups generally confirmed the quantitative findings. Discussion: Nietos Activos y Saludables intervention has the promise to increase Latino grandparents' knowledge about and self-efficacy in supporting grandchildren's PA. Future studies should test the impact of the intervention on grandparents' behavior and grandchildren's health outcomes using a randomized controlled trial.

African American communities are disproportionately impacted by prostate cancer (PCa) compared to other racial/ethnic groups. Whereas the incidence of PCa in Hispanic/Latino men is lower than the incidence in non-Hispanic/Latino White men, Hispanic/Latino men are more likely to be diagnosed with PCa in late stages, and less likely to be knowledgeable about PCa, resulting in significant disparities. We developed, culturally adapted, translated, implemented, and evaluated a PCa Cancer Advocacy Training in African American and Hispanic/Latino/a communities. Culturally and language specific content for African American and Hispanic/Latino/a patients on PCa causes, risk factors, epidemiology, detection, diagnosis, and treatment were delivered through a workshop and simultaneously broadcasted in Spanish in Los Angeles County (n = 29) and in English in Tallahassee, FL (n = 9). Pre- and posttest surveys assessed impact. Pre vs post differences were statistically significant in knowledge (5.0 ± 1.6 vs 6.3 ± 1.1) and advocacy intentions (3.9 ± 0.9 vs 4.3 ± 0.8), on correctly identifying warning signs for PCa (50% vs 87%), intent to inform and educate about PCa within the next 3 months (69% vs 95%), to ensure that high-quality research is sensitive to the priorities of patients (63% vs 84%), to help increase patient recruitment, compliance, and retention for clinical trials within the next month (62% vs 84%), intent to engage in PCa patient education within the next 3 months (67% vs 92%), and in engaging in PCa community outreach within the next 3 months (67% vs 94%). There were no significant differences due to race/ethnicity. The Cancer Advocacy Training led to increased knowledge, awareness, and intention to engage in advocacy regarding PCa in the next 3 months. Results suggest that delivering culturally and language specific educational information increases engagement of Hispanic/Latino/a and African American patient/community advocates.

Background: The importance of diversity in clinical trials is vital to ensure treatments and medications work and respond well for everyone. In contrast to other ethnic groups, AAs are disproportionately affected by various types of cancers in the U.S., such as prostate & pancreatic cancer, and have higher cancer mortality rates. Yet AA participation in cancer clinical trials remains extremely low. Black/African Americans make up 13.4% of the US population and have a clinical trial enrollment rate of less than 5%. In comparison, White/Caucasians make up about 67% of the US population and have a 75% enrollment rate in clinical trials and the Asian community makes up less than 6% of US population and have a 15% participation rate in clinical trials. Reported factors that have influenced Black/African American clinical trials enrollment rates are little awareness of clinical trials, religious beliefs, and access to health care barriers. Improving clinical trial participation among African Americans/African Nationals (AA/AN) is essential to reduce cancer health disparities because it gives opportunity to increased access to breakthrough cancer therapies and treatments. Methods: To address these disparities, we composed an AA/AN Clinical Trials manual to be distributed among these populations living in Los Angeles County (LAC). The AA/AN manual modules review: 1) Intro to Clinical Trials 2) Demographics 3) Types of clinical trials 4) Phases of clinical trials 5) Safety of clinical trials 6) The role of faith among AA communities and 7) Life during and after clinical trials. There is also a Call to Action to share the manual information with friends and family, to talk with one’s primary care physician and get screened, and to participate in clinical trials. The manual was culturally and linguistically adapted to deliver lay messages on clinical trials as needed, using graphs, infographics, and educational videos featuring clinical trials cancer researchers and experts. Results: 90 Churches in Los Angeles County serving AA/AN communities have been provided with avirtual copy of the Clinical Trials manual to be disseminated among their communities. Additionally, have participated in 7 major community health events in LAC to outreach and engage African American community members at which we have distributed 822 hard copy clinical trials manuals between November of 2021 and November of 2022. Conclusion: Involvement of faith-based communities in outreach and engagement strategies mayincrease cancer clinical trials participation among African American communities. The utilization of culturally sensitive and adapted educational materials may increase access to information on clinical trials and contribute to tackle clinical trials enrollment barriers affecting underserved minorities. Citation Format: Lourdes A. Baezconde-Garbanati, Carolina Aristizabal, Eduardo Ibarra, Cynthia Quince. Effectiveness of community outreach/engagement and faith-based strategies among African American & African Nationals to increase cancer clinical trials participation using a culturally tailored educational manual [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 1942.

Background: Certain groups are disproportionately impacted by prostate cancer (PCa) compared to other racial/ethnic groups such as Blacks. While the burden of PCa in Hispanics is low, there is limited understanding of the disparities in subpopulations of Hispanics. We developed and culturally adapted, and updated all the scientific data, translated, implemented and evaluated a Prostate Cancer Advocacy Training (PCAT) for Hispanic populations. Methods: Culturally and language specific content on PCa cause, risk factors, epidemiology, detection, diagnosis and treatment was delivered through a workshop and simultaneously broadcasted in Spanish in Los Angeles County (n=29) and in English in Tallahassee, Florida (n=9). Pre- and post-test surveys assessed impact. Results: The following pre vs. post differences were statistically significant (p < 0.05), in knowledge (5.0±1.6 vs 6.3±1.1) and advocacy intentions (3.9±0.9 vs 4.3±0.8). On correctly identifying warning signs for PCa (50% vs 87%), intent to inform and educate patients, family, and friends about PCa within the next three months, (69% vs 95%), to ensure that high quality research is sensitive to the priorities of patients (63% vs 84%), to help increase patient recruitment, compliance and retention for clinical trials within the next month (62% vs 84%), intent to engage in PCa patient education within the next three months, (67% vs 92%); and in engaging in PCa community outreach within the next three months, (67% vs 94%) There were no significant differences due to race/ethnicity. Conclusion: The PCAT led to increased knowledge, awareness, and intention to engage patients and community health workers in advocacy and engagement regarding PCa in the next three months. Results suggest that delivering culturally and language specific educational information increases engagement of Hispanic and African American patient/community advocates. This has implications for reducing cancer health disparities. Citation Format: Carolina Aristizabal. Training Minority Community Leaders on Prostate Cancer. Effect of an Educational Strategy in Los Angeles, CA & Tallahassee, FL [abstract]. In: Proceedings of the Annual Meeting of the American Association for Cancer Research 2020; 2020 Apr 27-28 and Jun 22-24. Philadelphia (PA): AACR; Cancer Res 2020;80(16 Suppl):Abstract nr 4346.