NODAT, recurrent and de novo NAFLD are common after LT but are not associated with signs of graft dysfunction, possibly due to the low frequency of IR and NASH. No correlation is observed between NAFLD and NODAT, MS, hypertriglyceridemia, obesity and IR. β-cell dysfunction and diabetes, however, are seen in most of the patients, possibly due to calcineurin inhibitor toxicity.

Objective: to study the association between musculoskeletal disorders in distal upper extremities (MSDUE) and the variable sex in the plastic industry. Method: cross-sectional study with 577 workers. The MSDUE was defined by the presence of pain in the previous twelve months, lasting for more than one week or having a monthly frequency, causing work restrictions or search for medical care, or severity ≥ 3 (from 0 to 5), in at least one of these regions: fingers, wrists, hands, forearms or elbows. Covariates of interest were: physical and psychosocial demands at work, sociodemographic and lifestyle-related variables, physical fitness and household work. Multiple logistic regression was used in order to investigate statistical interaction and presence of confounding variables. Results: MSDUE occurrence was higher among women, independently of the tested work-related and outside of work demands. Physical fitness was the interaction variable, and psychosocial demands was the confounding variable. Men who referred good physical fitness presented lower prevalence compared with those with poor physical fitness. Among women, good physical fitness was not enough to significantly reduce their high musculoskeletal morbidity. Conclusion: differences in workrelated exposure do not explain the higher morbidity among women. It is necessary to consider sex differences, either socially determined or related to biomechanics, resulting in distinct responses to work demands.

Introduction: Nonalcoholic steatohepatitis (NASH) associated or not with cirrhosis is the third leading indication for liver transplantation (LT) around the world. After transplants, NASH has a high prevalence and occurs as both recurrent and de novo manifestations. De novo NASH can also occur in allografts of patients transplanted for non-NASH liver disease. Objective: To evaluate recurrent or de novo NASH in post-LT patients. Method: A literature review was performed using search engines of indexed scientific material, including Medline (by PubMed), Scielo and Lilacs, to identify articles published in Portuguese and English until August 2016. Eligible studies included: place and year of publication, prevalence, clinical characteristics, risk factors and survival. Results: A total of 110 articles were identified and 63 were selected. Most of the studies evaluated recurrence and survival after LT. Survival reached 90-100% in 1 year and 52-100% in 5 years. Recurrence of NAFLD (steatosis) was described in 15-100% and NASH, in 4-71%. NAFLD and de novo NASH were observed in 18-67% and 3-17%, respectively. Metabolic syndrome, diabetes mellitus, dyslipidemia and hypertension were seen in 45-58%, 18-59%, 25-66% and 52-82%, respectively. Conclusion: After liver transplants, patients present a high prevalence of recurrent and de novo NASH. They also show a high frequence of metabolic disorders. Nevertheless, these alterations seem not to influence patient survival.