RESUMOIntrodução: Obstrução nasal crônica secundária a hipertrofia das conchas nasais inferiores é um sintoma comum, de importante morbidade em nosso meio. Várias técnicas cirúrgi-cas são descritas para os casos refratários aos tratamentos clínicos, porém, há controversas sobre qual delas é a mais efetiva e sujeita a menos complicações. Objetivo: Avaliar a eficácia, a segurança e exequibilidade do uso do ácido tricloroacético ambulatorial para o tratamento da hipertrofia dos cornetos inferiores. Método: Trabalho prospectivo com 29 pacientes que foram submetidos à técnica ambulatorial de infiltração de ácido tricloroacético a 30% submucosa dos cornetos inferiores, sob anestesia tópica. Foram avaliados os sintomas de rinorreia e obstrução nasal utilizando escala visual e analógica (EVA 010) pré cauterização e um ano pós procedimento. Resultados: Diminuição significativa da obstrução nasal e da rinorreia um ano pós procedimento. As complicações foram sinéquias leves em dois pacientes e sangramentos, de pequena monta, em quatro casos com resolução espontânea. Conclusão: O método proposto apresentou ótimos resultados quanto à obstrução nasal e rinorreia, pode ser realizado em ambiente ambulatorial, e vem nos mostrando ser de baixa complicação Palavras-chave: cauterização, obstrução nasal, ácido tricloroacético. Artigo Original SUMMARYIntroduction: Chronic secondary nasal obstruction, the hypertrophy of the inferior turbinates is a common symptom of great morbidity in our society. Several surgical techniques are described to cases refractory to medical treatments, however, there are controversy about which one of them is more effective and less subject to complications. Objective: Evaluate the efficacy, security and practicability of using ambulatory trichloroacetic acid to treat the hypertrophy of the inferior turbinates. Method: Prospective study with 29 patients submitted to the ambulatory technique of 30% trichloroacetic acid infiltration in the inferior turbinate's submucosa, under topic anesthesia. The symptoms of rhinorrhea and nasal obstruction were evaluated using the analogical and visual scale (AVS 010) precautery and one year post-procedure. Results: Significant nasal obstruction and rhinorrhea reduction one year post-procedure. The complications were light synechia in two patients and small bleedings in four spontaneous resolution cases. Conclusion: The proposed method showed excellent results concerning nasal obstruction and rhinorrhea, can be conducted in ambulatory environment, and has proved to be a lowcomplication method.
Background: Nonalcoholic fatty liver disease comprises a spectrum of lesions ranging from steatosis to cirrhosis, with nonalcoholic steatohepatitis being the progressive form of the disease. Alcohol intake, viral hepatitis and other liver diseases must be excluded. Liver biopsy is the gold standard for diagnosis of the disease and is the only method able to differentiate nonalcoholic steatohepatitis from simple steatosis, to grade inflammation and to stage fibrosis. Aims: To analyze the histopathological findings and evaluate interobserver agreement in biopsies previously diagnosed as steatosis or steatohepatitis. Methods: Seventy needle biopsies were analyzed according to Brunt et al. (4) , with modifications in the grading and staging components. Clinical data of patients were collected. Interobserver agreement was calculated based on histopathological findings. Results: Mild nonalcoholic steatohepatitis (grade 1) was the most common form. If fibrosis was detected, stage 1 was the most frequent. Interobserver agreement was very good for macrovesicular steatosis (K W = 0,82) and good for lobular inflammation (K W = 0,68) and fibrosis (K W = 0,73). Conclusions: The classification of Brunt et al., with modifications, can be applied to diagnosis not only of nonalcoholic steatohepatitis but also of nonalcoholic fatty liver disease, representing a reliable method for use in the daily practice of pathologists.
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