Aims Management of patients with mitral stenosis (MS) relies on accurate evaluation of the mitral valve area (MVA). Planimetry (MVA 2D ) is considered as the reference method but must be performed at the tips of the leaflets with the correct plane orientation and therefore requires experienced operators. Realtime three-dimensional echocardiography (RT3DE) may overcome this limitation but its usefulness for experienced when compared with less experienced operators has not been evaluated. In addition, superiority of RT3DE for the evaluation of commissural splitting after percutaneous mitral commissurotomy (PMC) is unknown. Methods and results 60 patients were prospectively evaluated by 2D and RT3DE before and after PMC by experienced operators. Before PMC, MVA 3D was slightly higher than MVA 2D (1.15 + 0.25 vs. 1.06 + 0.22 cm 2 , P ¼ 0.0001) but correlation between methods was excellent (r ¼ 0.73, P , 0.0001), mean difference was small (0.09 + 0.18 cm 2 ) and clinically meaningless (three patients misclassified, two of whom had borderline MS severity). After PMC, MVA 3D did not differ from and correlated well with MVA 2D (1.87 + 0.37 vs. 1.85 + 0.32 cm 2 , P ¼ 0.36; r ¼ 0.76, P , 0.0001; mean difference 0.03 + 0.24 cm 2 ). Twenty-five additional patients were also evaluated both by an experienced and a less experienced operators. Bland-Altman analysis showed the better agreement between MVA 3D measured by the less experienced operator and MVA 2D measured by the experienced operator than between MVA 2D measured by the less experienced and the experienced operators (mean difference 0.03 + 0.34 vs. 20.13 + 0.46 cm 2 , P ¼ 0.03). When compared with RT3DE, 2DE underestimated the degree of commissural opening in 33% of patients and agreement between methods was weak (k ¼ 0.41). Conclusion RT3DE provides accurate MVA measurements similar to 2D planimetry performed by experienced operators. Thus, it does not provide a real advantage for experienced operators, whereas it seems particularly helpful for less experienced operators. In addition, RT3DE improves the description of valvular anatomy.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.