The worldwide increasing number of reports related to new cases of Breast Implant-associated Anaplastic Large Cell Lymphoma (BIA-ALCL) raises the interest of the scientific community in understanding the pathophysiology and the prognosis of these patients. This material presents the impact that BIA-ALCL exerts on the reconstructive options for patients who have undergone mastectomy. The research is based on data obtained from the analysis of a group of patients who have undergone 71 surgeries performed within the National Breast Reconstruction Program between 2015 and 2019. The statistical analysis revealed that 35.14% of the patients that were examined during the breast reconstruction consult refused the use of alloplastic techniques by invoking the potential associated risks described in the insufficient documentation of BIA-ALCL pathophysiology. Improving BIA-ALCL detection and reporting systems has led to an accelerated increase in the number of new diagnosed cases, determining the patients� reticence towards the use of alloplastic reconstructive techniques.

Introduction: The optimization of the breast reconstruction treatment protocols and the introduction of state-subsidized national programs are global priorities. The present paper presents the results obtained within the National Program of Breast Reconstruction at the "Bagdasar-Arseni" Emergency Clinical Hospital, highlighting the advantages and disadvantages of the surgical techniques used. Materials and Methods: The results obtained after 71 surgical interventions were used for the study. The methodology used involved the use of demographic data, patient history, and the description of the surgical methods and techniques that were used. Results: Among the main results, the paper highlights the fact that mammary reconstruction by using the 'expander-implant' surgical technique was 5 times more frequent than the "implant-myocutaneous flap" technique. Post-operative complications have been present in 57% of the patients who associate comorbidities. Breast reconstruction using the TRAM (transverse rectus abdominis muscle 1) flap was the rescue solution for severe complications. Conclusions: The TRAM flap was proven to be the best technique in the treatment of diffi cult cases. Carrying out these statistical analyzes related to projects of a national scale form the solid foundation of documented studies that bring a signifi cant contribution to the development of the Romanian medical system.

Increasing the incidence of breast cancer worldwide is an alarming factor for the medical community and also an additional reason for accountability. Oncological treatment, followed by subsequent reconstructive stages, are traumatic events that without a doubt exert their adverse effects on the quality of life of these patients. The reconstruction of the nipple-areola complex represents the final element in the treatment of patients who have suffered from cancer breast and must follow basic principles such as: reproducibility, efficacy, short duration of treatment and low rate of complications. The present material presents the various surgical techniques dedicated to the reconstruction of the nipple-areola complex, presenting their advantages and disadvantages based on a 5-year study. The use of single-stage techniques associated with medical tattooing were the main factor in increasing the satisfaction of the patients included in the research.

Objectives: The paper presents the reconstructive options of the lower eyelid region in patients who have benefited from the excision of basal cell carcinomas. Methods: The study was based on the clinical and evolutionary particularities analyzed in a series of cases, the patients benefiting from excision and reconstruction for the treatment of basal cell carcinomas located at the level of the orbital region. Results: Following the surgical treatment, the local evolution was favorable with a good functional recovery. The aesthetic results were strongly influenced by the stage of the neoplasm, the final aspect being satisfactory for the patients included in the study. Conclusion: Early diagnosis and rapid and effective surgical treatment are associated with favorable results from a functional and aesthetic point of view. Delayed surgery and treatment of relapses are associated with increased risks and inferior results.

Objective. The current paper presents an interesting case of facial reconstruction after the excision of a giant basal cell carcinoma located in the orbitofrontal region. Methods. Performing the excision while securing the appropriate oncologic safety margin has determined the appearance of a soft tissue defect that required a complex reconstruction using three regional flaps: frontal, temporal fascial and temporal muscle flaps. Results. After the excision and reconstruction in a single surgical stage, the postoperative result was favorable, the 12 months assessment showing that the patient was satisfied with the aesthetic aspect. Conclusion.Including the orbital exenterations in the excisional treatment of giant neoplasms located in the facial region requires a complex reconstructive plan. The surgical team has to consider the relief of the anatomical structures that are targeted, as well as the necessity of achieving satisfactory aesthetic results while ensuring oncological radicality.