Progressive macular thickening under the array was common and corresponded to decreased electrode-retina gap over time. By month 12, the array was completely apposed to the macula in approximately half of the eyes.
Management of a ruptured hepatocellular adenoma during pregnancy is a rare and potentially life-threatening entity. Few case reports have described management of the pregnant patient who presents in haemorrhagic shock secondary to a ruptured liver adenoma. A 30-year-old primigravid woman at 31 weeks pregnant presented with abdominal pain and fetal bradycardia. After stat caesarean delivery of the infant, she had continued hemoperitoneum and was in shock secondary to an undiagnosed ruptured liver mass. General surgery was consulted intraoperatively and performed an exploratory laparotomy, packing and temporary closure. She was subsequently taken to interventional radiology (IR) for angioembolisation of the left hepatic artery. After stabilisation, she underwent formal abdominal closure. Management of a ruptured hepatocellular adenoma in pregnancy requires urgent multidisciplinary care including obstetrics gynaecology, general surgery and IR.
Introduction: Metastatic lesions to the ovary, also known as Krukenberg tumors, account for approximately 5-30% of ovarian neoplasms. The location of primary sites and survivability widely varies. Patients with a pancreatic primary site have lower survival rates compared to other primary sites such as colon and breast. Despite this dismal outcome, there is a paucity of data examining the pancreas as the primary site and it is associated clinical, radiologic, and pathologic features. Case Report: Four women who presented with severe abdominal pain were found to have pancreatic cancer that metastasized to the ovary. Only one woman did not have metastasis to the ovary at time of presentation. Three of the four had bilateral ovarian involvement. One woman's mass was deemed unresectable while the other three women had cytoreductive surgery including bilateral salpingooophorectomy. Imaging, pathology, and tumor markers were trended over time. Discussion: Characteristics which may support a pancreatic origin of Krukenberg tumors include bilateral, large, multiloculated cystic ovarian masses, surface ovarian involvement, and specific immunohistochemical staining patterns. Comprehensive clinical, radiologic, and pathologic evaluation is essential as identification of pancreatic Krukenberg tumors has a significant impact on patient treatment and prognosis.
ObjectiveEndocervical curettage (ECC) during colposcopy is recommended in certain circumstances; however, diagnostic use remains unclear. We evaluate the utility of ECC among patients with non-fully visualized squamocolumnar junction (SCJ) and certain patient socioeconomic factors.MethodsRetrospective chart analysis was completed for patients aged older than 21 years who underwent a colposcopy at 2 study sites between 2012 and 2021. Demographics and histopathologic results were analyzed.ResultsA total of 1,516 colposcopies were reviewed; 73.8% (n = 1,119) had an ECC with colposcopy. Of those, 92.1% (n = 1,031) had benign ECC whereas 13.9% (n = 156) had a positive ECC at time of colposcopy. Most patients with benign ECC had benign/low-grade squamous intraepithelial lesion pathology on colposcopy biopsy (82.3%; n = 914; p < .001), and most patients with high-grade squamous intraepithelial lesion (HSIL) on ECC had HSIL on colposcopy biopsy (63.4%; n = 52; p < .001) However, when looking at patients with high-grade pathology on colposcopy biopsy, it was seen that most had benign or low-grade squamous intraepithelial lesion on ECC (79.5%; n = 205; p < .001). Most patients with adequately visualized SCJ on colposcopy were noted to have HSIL on biopsy and negative ECC (73%; n = 81; p < .001). This result was similar in patients with non-fully visualized SCJ, although not statistically significant. When stratified by socioeconomic status, most patients with high-grade lesions had a benign ECC.ConclusionsEndocervical curettage has been described to increase the identification of high-grade lesions at time of colposcopy. This descriptive study shows that many high-grade lesions at time of excisional procedure had a benign ECC on colposcopy, with no demonstrated clear additional utility in high-risk groups.
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