The trend toward personalized approaches to health and medicine has resulted in a need to collect high-dimensional datasets on individuals from a wide variety of populations, in order to generate customized intervention strategies. However, it is not always clear whether insights derived from studies in patient populations or in controlled trial settings are transferable to individuals in the general population. To address this issue, a longitudinal analysis was conducted on blood biomarker data from 1032 generally healthy individuals who used an automated, web-based personalized nutrition and lifestyle platform. The study had two main aims: to analyze correlations between biomarkers for biological insights, and to characterize the effectiveness of the platform in improving biomarker levels. First, a biomarker correlation network was constructed to generate biological hypotheses that are relevant to researchers and, potentially, to users of personalized wellness tools. The correlation network revealed expected patterns, such as the established relationships between blood lipid levels, as well as novel insights, such as a connection between neutrophil and triglyceride concentrations that has been suggested as a relevant indicator of cardiovascular risk. Next, biomarker changes during platform use were assessed, showing a trend toward normalcy for most biomarkers in those participants whose values were out of the clinically normal range at baseline. Finally, associations were found between the selection of specific interventions and corresponding biomarker changes, suggesting directions for future study.

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Parce qu'elle utilise des générateurs électriques de rayons X pour le radiodiagnostic chez l'animal, la profession vétérinaire est également soumise à la réglementation concernant la radioprotection. Ainsi la législation impose à toutes les personnes travaillant à proximité de ces appareils des obligations techniques, d'organisation et administratives. Elle implique aussi la formation d'une personne compétente en radioprotection et en définit le rôle. La reconnaissance d'une spécificité vétérinaire par rapport aux activités nucléaires, industrielles et de médecine humaine est soulignée.

between investigative team and funder, which provided support in the form of salaries, and was involved in the study design, data collection and analysis, decision to publish, and preparation of the manuscript. "