ABSTRACT:The objective of this study was to determine the gamma-glutamyl transferase (GGT) levels and its relationship with diarrhea and passive transfer of immunity in Holstein calves within 24 hours and 30 days of life from Leopolis municipality, the north Parana region. Colostrum is rich in immunoglobulins and vital for immunity to newborn calves, since bovine placenta does not allow the passage of immunoglobulin to the fetus. Calves undergo various challenges that can lead to disease and death in the first month of life, including diarrhea. Diarrhea has a multifactorial etiology, and the passive immunity transferred through ingestion of colostrum is able to protect the calf against many of these etiologic agents. GGT measurements indirectly infer the amount of immunoglobulin ingested by the calf. Higher serum GGT levels (381.72 IU / L) were found at 24 hours, and a significant reduction was observed at 30 days (66.22 IU / L). When the presence or absence of diarrhea was associated with GGT levels above and below 200 IU / L, no statistical significance (P> 0.05) was observed, since 80% of animals with diarrhea had serum GGT levels higher than 200 IU / L. Under the conditions of this study, there was no relationship between the GGT concentration and the occurrence of diarrhea, and no mortality was observed despite some animals presented diarrhea.
ABSTRACT:The objective of this study was to determine the gamma-glutamyl transferase (GGT) levels and its relationship with diarrhea and passive transfer of immunity in Holstein calves within 24 hours and 30 days of life from Leopolis municipality, the north Parana region. Colostrum is rich in immunoglobulins and vital for immunity to newborn calves, since bovine placenta does not allow the passage of immunoglobulin to the fetus. Calves undergo various challenges that can lead to disease and death in the first month of life, including diarrhea. Diarrhea has a multifactorial etiology, and the passive immunity transferred through ingestion of colostrum is able to protect the calf against many of these etiologic agents. GGT measurements indirectly infer the amount of immunoglobulin ingested by the calf. Higher serum GGT levels (381.72 IU / L) were found at 24 hours, and a significant reduction was observed at 30 days (66.22 IU / L). When the presence or absence of diarrhea was associated with GGT levels above and below 200 IU / L, no statistical significance (P> 0.05) was observed, since 80% of animals with diarrhea had serum GGT levels higher than 200 IU / L. Under the conditions of this study, there was no relationship between the GGT concentration and the occurrence of diarrhea, and no mortality was observed despite some animals presented diarrhea.
Resumo: Urolitíase é uma doença metabólica de ruminantes castrados e não castrados. A formação de urólitos provoca trauma e obstrução do trato urinário. A nutrição e o manejo são os principais fatores predisponentes. Este artigo descreve um caso de litíase urinária obstrutiva em touro Nelore em Rolândia estado do Paraná, Brasil. Um touro Nelore de 4,5 anos de idade foi enviado para um matadouro frigorífico, Paraná, Brasil, apresentando perda de apetite há cinco dias. No Serviço de Inspeção Estadual (SIP) a carcaça foi condenada, devido a achados consistentes com uremia e ruptura da bexiga com uroperitonio e peritonite. As amostras de rins foram coletadas e submetidas à análise bacteriológica e fixados em formol a 10%, processados para histologia, embebidos em parafina, cortados em cinco micrometros de espessura e corados com hematoxilina e eosina (HE). Observou-se múltiplos abscessos, na superfície de corte do rim e dilatação dos cálices renais, presença de urólitos e hidronefrose. Na microscopia do rim foi observado áreas de intensa infiltração intersticial de neutrófilos e linfócitos. Ureia elevada (147 mg / dL), creatinina (12 mg / dL), Ca (7,4 mg / dL) e P (12,1 mg / dL). O diagnóstico de litíase urinária obstrutiva foi baseado a partir de lesões macroscópicas. Relatos de urolitíase obstrutiva em touros no Brasil são raras. Proteus mirabilis produz urease. A urease é um fator determinante para a colonização, litíase urinária e pielonefrite aguda grave. Este relato descreve Proteus mirabillis para determinar os fatores que levaram a formação de urolitíase no touro Nelore.Palavras chaves: urolitíase obstrutiva, uroperitonio, bovino.
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