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ABSTRACT.The mineral exploration is a complex activity that should involve a combination of direct and indirect techniques of geological investigation. The growing demand for base metals in the national and international market provides the revaluation of mineral occurrences that can become deposits and mines. This paper presents the results of the electrical resistivity and induced polarization geophysical methods in azimuthal arrangement, applied in a mineral occurrence of disseminated copper sulfides, previously studied through trenches and core drilling, located in the Camaquã Sedimentary Basin, Rio Grande do Sul State, Brazil. The inversion models indicate the coincidence of high chargeability and low resistivity values. The integration of geophysical data permitted the elaboration of 3D attributes visualization models for the mineralization enclosed in volcanic tuffs. The integrated geophysical and geological analysis indicates the potential of a new mineralized area.Keywords: ore, sulfide, copper, geophysics, modeling. RESUMO.A pesquisa mineralé uma atividade complexa, que deve envolver preferencialmente a combinação de técnicas diretas e indiretas de investigação geológica.A demanda crescente por metais base no mercado nacional e internacional proporcionam a reavaliação de ocorrências minerais, que podem ser convertidas em depósitos e minas. Este trabalho apresenta os resultados da aplicação dos métodos geofísicos de eletrorresistividade e da polarização induzida em arranjo azimutal, numa ocorrência mineral de sulfetos de cobre disseminados, previamente estudada por meio de trincheiras e sondagem testemunhada, localizada na Bacia Sedimentar do Camaquã, Estado do Rio Grande do Sul. Os modelos de inversão indicam o predomínio de alta cargabilidade coincidente com valores de baixa resistividade. A integração dos dados geofísicos possibilitou a elaboração de modelos de visualização 3D para análises dos atributos associadosà mineralização, alojada em tufos vulcânicos. A análise integrada de dados geofísicos e geológicos aponta para uma região potencialmente mineralizada.Palavras-chave: minério, sulfeto, cobre, geofísica, modelagem.

Geophysical methods have a varying degree of potential for detailed characterization of landslides and their dynamics. In this study, the application of four well-established seismic-based geophysical techniques, namely Ambient Noise Interferometry (ANI), Horizontal to Vertical Spectral Ratio (HVSR), Multi-Channel Analysis of Surface Waves (MASW) and Nanoseismic Monitoring (NM), were considered to examine their suitability for landslide characterization and monitoring the effect of seasonal variation on slope mass. Furthermore, other methods such as Ground Penetrating Radar (GPR) and DC Resistivity through Electrical Resistivity Tomography (ERT) were also used for comparison purpose. The advantages and limitations of these multiple techniques were exemplified by a case study conducted on Sobradinho landslide in Brazil. The study revealed that the geophysical characterization of the landslide using traditional techniques (i.e., GPR, ERT and MASW) were successful in (i) the differentiation between landslide debris and other Quaternary deposits, and (ii) the delineation of the landslide sliding surface. However, the innovative seismic based techniques, particularly ambient noise based (HVSR and ANI) and emitted seismic based (NM), were not very effective for the dynamic monitoring of landslide, which might be attributed to the short-time duration of the data acquisition campaigns. The HVSR was also unsuccessful in landslide site characterization i.e., identification of geometry and sliding surface. In particular, there was no clear evidence of the light seasonal variations, which could have been potentially detected from the physical parameters during the (short-time) ambient noise and microseismic acquisition campaigns. Nevertheless, the experienced integration of these geophysical techniques may provide a promising tool for future applications.

ResumoEstudos de pesquisa mineral são fundamentais para o reconhecimento e a incorporação de novas reservas. Esse trabalho apresenta os resultados de aplicação do método geofísico da eletrorresistividade numa ocorrência mineralizada em carbonatos de cobre, por meio da técnica de caminhamento elétrico em arranjo azimutal. A área de estudos está inserida na bacia sedimentar do Camaquã, formada por um conjunto de unidades estratigráficas sedimentares e vulcanogênicas, onde são descritas diversas ocorrências cupríferas. A presença de azurita e malaquita em fraturas e zonas de maior porosidade em arenito encaixante define a geologia local. Os modelos de inversão revelam anomalias circulares de resistividade moderada para até 25m abaixo da ocorrência aflorante e anomalias de baixa resistividade em profundidades abaixo de 25m, além de áreas adjacentes com alta resistividade. Indicadores de mineralização descritos para ocorrências de cobre estudadas, no âmbito da bacia sedimentar do Camaquã, ocorrem na área de estudos e permitem caracterização em termos de resistividade elétrica. Áreas com silicificação apresentam alta resistividade, enquanto que valores intermediários são atribuídos a zonas com carbonatação e, finalmente, áreas de baixa resistividade, provavelmente, indicam concentrações de sulfetos disseminados.Palavras-chave: Eletrorresistividade, arranjo azimutal, sulfeto, cobre pórfiro, minério. Abstract Mineral research studies are fundamental for the recognition and incorporation of new reserves. This paper presents the results of an application of the Electrical Resistivity geophysical method to a mineral occurrence of copper carbonates, by an electrical profiling technique in an azimutal array. The parameter of physical electric resistivity was measured, using the Electrical Resistivity method and the technique of electrical profiling. This study area is inserted in the Camaquã

Extensively drug-resistant tuberculosis (XDR-TB), which is TB resistant to isoniazid and rifampin plus one fluoroquinolone and a second-line injectable drug, represents an obstacle for the treatment and control of TB. Previously, we reported four XDR-TB cases and a high proportion of the Beijing genotype among multidrug-resistant TB (MDR-TB) isolates in the state of Valle del Cauca, Colombia (3), where a MDR-TB hot spot had been identified (7). According to the information of the local TB program, to date 21 XDR-TB cases have been diagnosed in the country, 14 of which were from this state.With Resistance profiles were identified using the proportion method on 7H10 agar (6) and confirmed by a supranational laboratory. Molecular characterization of the isolates was performed by spoligotyping (5) and 24-locus variable-number tandem-repeat (VNTR) typing (8). GenoType MTBDRplus and -sl assays (Hain Lifescience GmbH) were applied to identify mutations associated with resistance to firstand second-line anti-TB drugs. Shared types and lineages of Myco-