Background Surveys report low frequencies of sexual history (SH) obtained in primary care. Sexually transmitted infections incidence can be reduced with timely screening. It is important to determine whether providers obtain thorough SH and to identify needs for improvement. Aim To evaluate the frequency and depth of SH taking in primary care. Methods In this cross-sectional cohort study, 1,017 primary care visits were reviewed (1,017 adult patients, female 55.26%). 417 patients were seen by male providers and 600 patients were seen by female providers. Multivariate ordered and logit models were deployed. Main Outcome Measures The primary outcome measures included SH taking rates and completeness based on the 5 P model as described by the Centers for Disease Control and Prevention. Results All components of SH were explored in 1.08% of visits. Partial SH was obtained in 33.92% of visits. No SH was taken in the majority of visits (65%). SH was more likely to be taken from female patients than from male patients (P < .001), and was less likely to be obtained from older patients as compared to younger individuals (P < .001). There was no significant difference in SH taking between male and female providers (P = .753). The provider title and the level of training were found to be independent predictors of SH taking (P < .001). Clinical Implications The results of this study highlight an unmet need for more comprehensive and consistent SH taking amongst providers, particularly in high-risk settings, so that SH can be used as a valuable tool in preventive care. Strengths & Limitations To the best of our knowledge, this is the largest study to date examining SH taking in the primary care setting. Limitations include the retrospective study design, lack of generalizability to other hospitals, and inconsistencies in available data. Conclusion The SH taking rates in primary care clinics are globally low with a variation depending on the provider position or level of training, provider gender, and patient age.

Cancer is the first cause of death by disease in childhood globally. The most frequent types of cancers in children and adolescents are leukemias, followed by brain and central nervous system tumors and lymphomas. The recovery rate of cancer in children is around 80% in developed countries and up to 30% in developing countries. Some of the main causes of complications in children and adolescents with cancer are respiratory viral infections, mainly in bone marrow-transplanted patients. Respiratory viruses have been detected in the bronchoalveolar lavage or nasal wash specimens from cancer patients with or without respiratory illness symptoms. Human metapneumovirus (HMPV) is within the ten most common viruses that are encountered in samples from pediatric patients with underlying oncology conditions. In most of cases, HMPV is found as the only viral agent, but co-infection with other viruses or with bacterial agents has also been reported. The discrepancies between the most prevalent viral agents may be due to the different populations studied or the range of viral agents tested. Some of the cases of infection with HMPV in cancer patients have been fatal, especially in those who have received a hematopoietic stem cell transplant. This review seeks to show a general view of the participation of HMPV in respiratory illness as a complication of cancer in childhood and adolescence. Keywords: pediatric cancer infections; HMPV; fatal cases in HSCT patients Childhood Cancer Global SituationCancer is the first cause of death by disease in children around the world. The five-year rate of survival of children who have cancer is up to 80% in developed countries, but for developing countries, the survival rate is less than 30% [1].According to a study based in cancer registries from 52 countries, the types of cancer in childhood (0-19 years old) during 2001-2010 were leukemia, lymphoma, central nervous system tumors, sympathetic nervous system tumors, retinoblastoma, renal tumors, hepatic tumors, bone tumors, soft tissue sarcomas, germ cell and gonadal tumors, epithelial tumors, and melanomas. The most frequent cancers in children of 0-14 years are leukemia, followed by lymphoma; meanwhile, for the ages of 15-19, the most prevalent is lymphoma, followed by leukemia [2].Cancer in childhood comprises only 1% of the total cancer cases worldwide; however, it has a dramatic impact. Recently the years of life lost due to cancer in childhood (0-19 years old) were calculated with global cancer registries in 2017, with a result of more than 11 million years [3].