A 15-year-old female presented to the emergency department of a level 1 trauma centreafter being involved in a high-speed motor vehicle accident. The patient underwent a contrast-enhanced CT scan of the abdomen and pelvis obtained with a 60–70 s delay as part of the institution’s polytrauma protocol. The CT scan demonstrated multiple hepatic lacerations and a filling defect in the suprahepatic inferior vena cava adjacent to the cavoatrial junction. Inferior vena cava thrombus secondary to blunt abdominal trauma is extremely rare, and to our knowledge, this is the first reported case of acute thrombus diagnosed by CT at the time of initial injury. There is limited literature on management of this entity. Possible treatments range from conservative approaches to anticoagulation and placement of IVC filters.
Prothrombotic conditions are known risk factors for porencephalic cyst formation and cerebral vein thrombosis. Intracerebral hemorrhage is a potential complication of a cerebral vein thrombosis. Porencephaly is a risk factor for intracerebral hemorrhage and cerebral vein thrombosis formation. We present the case of an adult patient with a past medical history of epilepsy and congenital porencephalic cyst with de novo mutation of the COL4A1 gene who presented for episodes of generalized tonic-clonic seizure after a substantial symptom-free period. A brain CT scan showed an intracerebral hemorrhage with porencephalic cyst and superior sagittal sinus thrombosis despite negative thrombophilia work-up. A CT perfusion study, CT angiography, and brain MRI confirmed the diagnosis. The cause-and-effect relationship between porencephalic cysts, cerebral venous thrombosis, and intracerebral hemorrhage is still not clear in the literature.
6 months' follow-up in 16 (50%) patients, while at 12 months' follow-up this response decreased to 13 (40%) tumours. 6 (18%), patients showed approximately 60-90% reduction of arterialization, while only in 2 (0.06%) patients no response was observed and in one patient disease progression was observed at three months followup. Conclusions: In terms of the effect on the tumour response, combined TACE + PEI therapy was an effective in controlling the disease process.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.