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The giving of 3,3',5-triiodo-l-thyronine in the drinking water produces marked metabolic and circulatory changes. These effects produce hypertrophy of the heart. The water content of the hypertrophied hearts does not change. The hypertrophy of the heart is obtained in both rats and mice. In the rat, following removal of the T-3, there is a return of the heart to approximately the normal size.

rPHERE have been several instruments designed to measure concentrations of gases of physiological interest by infrared absorption, which do not involve the use of a spectrometer. The first of this type of instrument was designed by Pfund (3) and used by Pfund and Gemmill (4) to measure the metabolic exchange of carbon dioxide from yeast and muscle. The developments in this field have been reviewed by Williams (5). More recently, Fowler (1) has described an instrument with rapid rate of response for physiological work, and Miller and Russell (2) have developed a single-tube instrument with novel characteristics. However, most of these instruments involve the use of two tubes and are rather large and expensive. It was thought that a simpler and less expensive instrument might be developed.

describing an all-glass rotating evaporator has prompted this report on a similar apparatus which has been in use in this author's laboratory for some months. The apparatus described operates on the same essential principle as Volk's-rotation about a semiball joint-but it has the advantage of being a continuousfeed device and is much easier and much less expensive to construct.