Background: Establishing a diagnosis of giant cell arteritis, or indeed ruling it out, may be difficult. We describe an evaluation of temporal artery colour duplex ultrasound as first line investigation in patients with suspected giant cell arteritis. Methods: A retrospective cohort study of all patients undergoing colour duplex ultrasound for suspected giant cell arteritis between January 2005 and January 2014 was undertaken at a teaching hospital. A minimum clinical follow-up of three months was required. Patients were classified on the basis of ultrasound reports, using described features such as a halo sign or arterial wall thickening and clinical diagnosis of giant cell arteritis after at least 3 months follow-up, determined by the treating physician. The relationship of colour duplex ultrasound to a final clinical diagnosis of giant cell arteritis was analysed. Results: A total of 87 patients underwent colour duplex ultrasound: 36 (41%) had clinically confirmed giant cell arteritis at 3-month follow-up. The positive predictive value of colour duplex ultrasound for a clinical diagnosis at 3 months was 97% (95% confidence interval (CI) 93 to 99%) and negative predictive value 88% (95% CI 76 to 95%). Sensitivity was 81% (95% CI 64 to 92%) and specificity 98% (95% CI 90 to 100%). Conclusions: A high positive and negative predictive value of arteritis on colour duplex ultrasound indicates that temporal artery biopsy may be unnecessary in suspected giant cell arteritis, particularly where clinical suspicion of giant cell arteritis is high or low. Keywords 269clinical providers and archived paper medical records as necessary. For the purposes of this study, a clinical diagnosis of GCA made by a consultant rheumatologist, alone or in collaboration with other specialists, after a minimum of 3 months of follow-up, served as the reference or 'gold' standard for a diagnosis of GCA. The American College of Rheumatology (ACR) criteria for GCA were also used to classify all cases for comparison. 4 CDUS was performed on all patients. Examinations were performed by one of two consultant radiologists experienced in vascular ultrasound. Radiologists were not blinded to the suspicion of GCA or clinical data including laboratory test results. Studies were performed using a high-resolution multi-D linear array transducer VFX 13-5 MHz with a Doppler frequency above 6.5 MHz (Hitachi HA700, Hitachi Medical Systems). This probe gives a high frequency range up to 13 MHz and is designed for high resolution imaging of superficial structures. Each patient was examined using standard settings (frequencies of 13.0 MHz for B-mode and 9.0 MHz for colour-mode scanning).Ultrasound examination of the temporal arteries included longitudinal and transverse views of the common superficial temporal arteries and the frontal and parietal branches on both sides as completely as possible (dynamic range 45-50 dB, wall filter low or general, pulse repetition frequency 2250 Hz). The temporal and common carotid artery wall thicknesses on both s...

Tibial artery PSVs increase, correlate with an increase in ABI, and fall within or near confidence intervals for normal controls after above-knee endovascular interventions. After endovascular intervention, tibial artery PSVs can supplement ABI as an objective performance measure in patients with and in particular without compressible tibial arteries.

P ¼ .02), and the odds of amputation were higher in the Direct Care group at 2 years (OR, 0.34; 95% CI, 0.13-0.91; P ¼ .03). Odds of death, AMI, and amputation were otherwise not significantly different between the two groups.Conclusions: Individuals treated under the FFS system were significantly more likely to receive a procedure for PAD than those in the salaried system. Although the factors driving variation in the odds of intervention are certainly multifactorial, differences in reimbursement incentives in the FFS and salary systems may potentially play a role. That these differences are seen primarily in individuals with claudication, where medical and surgical management are felt to be more equivalent and greater opportunity exists for provider preference to influence management decisions, supports this theory.

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