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Chitosan is one of the most widely used biopolymers in wound healing applications due to its diverse physicochemical properties. On the other hand, curcumin possesses unique features like anti-microbial, anti-oxidant, immunomodulatory, anti-diabetic etc. Curcumin extract was isolated from turmeric using solvent extraction method and biopolymeric hydrogel was synthesized using varying compositions of chitosan polymer. Fourier Transform Infrared Spectroscopy and Gas chromatography-mass spectrometry were used for the evaluation of the developed extract and the developed hydrogel. FTIR spectra of biopolymeric chitosan hydrogel, curcumin extract and curcumin-loaded hydrogel showed characteristic absorption bands at 3338 cm-1 due to O-H stretching while the unique peaks of chitosan at 1634 cm-1 (Amide I), 1414 cm-1 (Amide III) were also observed in the hydrogel. Curcumin extract showed the characteristic peaks at 2973 cm-1 -CH3 stretching and 1045 cm-1 C-OH stretching. GC-MS analysis of curcumin extract showed a single major peak at retention time of 1.41 min; combined spectra analysis of the same peak showed more than twenty-five compounds. NIST database analysis report revealed that curcumin extract and curcumin standard showed almost similar compounds in terms of molecular weight and chemical formula.

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