BACKGROUND There are several well recognised scoring systems for evaluation and prognostication of critically ill patients. While APACHE II (Acute Physiology and Chronic Health Evaluation II) scoring system uses a point score based on physiologic parameters, age and previous health status, the SOFA (Sequential Organ Failure Assessment) scoring system takes into account the organ failure in critically ill patients. In the assessment of critically ill patients with suspected multiorgan dysfunction admitted in ICU, the role of SOFA in predictive validity for in-hospital mortality is being widely discussed. MATERIALS AND METHODS This was a prospective study undertaken in emergency ICU of a government tertiary care hospital in North East India over a period of one year to prognosticate the patients by using two different established scoring systems, e.g. SOFA and APACHE II. RESULTS The results showed that serial measurement of SOFA score during first week is a very useful tool in predicting the outcome especially on the day 3. The APACHE II score on day of admission, though reliable, was not very effective in predicting the mortality rate in our setup. CONCLUSION Serial measurement of SOFA score during first week is very useful tool in predicting the outcome of sepsis patients in ICU and better than admission APACHE II scoring in predicting mortality.

BACKGROUNDSepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection, which is one of the most important cause of mortality and morbidity in critically ill patients. In this study, comparative analysis of various parameters of survivors and non-survivors of sepsis has been done.