Objectives To evaluate the effect of a forest experience on the levels of depression of alcoholics. Methods Prior to the study, 92 alcoholics were divided into treatment and control groups. During the summer of 2009, the treatment group participated in a series of forest therapy programs, while the control group followed their normal daily routines. Both groups were re-tested upon completion of the program by the treatment group and the depression levels compared. Results There was a significant improvement in the depression level of alcoholics who had participated in the forest camp program (treatment group). Those participants in their 40s who had severe levels of depression at the beginning of the program showed the most significant improvement during the program experience. Conclusion The forest therapy camp experience can considerably reduce and ameliorate the depression levels of alcoholics.

The risk of cardiovascular disease is known to be increased in obstructive sleep apnea syndrome (OSAS). Its mechanism can be explained by the observation that the sympathetic tone increases due to repetitive apneas accompanied by hypoxias and arousals during sleep. Heart rate variability (HRV) representing cardiac autonomic function is mediated by respiratory sinus arrhythmia, baroreflex-related fluctuation, and thermoregulation-related fluctuation. We evaluated the heart rate variability of OSAS patients during night to assess their relationship with the severity of the symptoms. We studied overnight polysomnographies of 59 male untreated OSAS patients with moderate to severe symptoms (mean age 45.4± 11.7 yr, apnea-hypopnea index [AHI]=43.2±23.4 events per hour, and AHI >15). Moderate (mean age 47.1±9.4 yr, AHI=15-30, n=22) and severe (mean age 44.5±12.9 yr, AHI >30, n=37) OSAS patients were compared for the indices derived from time and frequency domain analysis of HRV, AHI, oxygen desaturation event index (ODI), arousal index (ArI), and sleep parameters. As a result, the severe OSAS group showed higher mean powers of total frequency (TF) (p=0.012), very low frequency (VLF) (p= 0.038), and low frequency (LF) (p=0.002) than the moderate OSAS group. The LF/HF ratio (p=0.005) was higher in the severe group compared to that of the moderate group. On the time domain analysis, the HRV triangular index (p=0.026) of severe OSAS group was significantly higher. AHI was correlated best with the LF/HF ratio (rp=0.610, p<0.001) of all the HRV indices. According to the results, the frequency domain indices tended to reveal the difference between the groups better than time domain indices. Especially the LF/HF ratio was thought to be the most useful parameter to estimate the degree of AHI in OSAS patients.

Leaves are the final site of salinity perception through the roots. To better understand how wheat chloroplasts proteins respond to salt stress, the study aimed to the physiochemical and comparative proteomics analysis. Seedlings (12-days-old) were exposed to 150 mM NaCl for 1, 2, or 3 days. Na(+) ions were rapid and excessively increase in roots, stems and leaves. Photosynthesis and transpiration rate, stomatal conductance, and relative water content decreased whereas the level of proline increased. Statistically significant positive correlations were found among the content of hydrogen peroxide, activity of catalase, and superoxide dismutase under salt stress in wheat. Protein abundance within the chloroplasts was examined by two-dimensional electrophoresis. More than 100 protein spots were reproducibly detected on each gel, 21 protein spots were differentially expressed during salt treatment. Using linear quadruple trap-Fourier transform ion cyclotron resonance (LTQ-FTICR) hybrid mass spectrometry, 65 unique proteins assigned in the differentially abundant spots. Most proteins were up-regulated at 2 and 3 days after being down-regulated at 1 day. Others showed only slight responses after 3 days of treatment, including Rubisco, glutamate dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, isocitrate dehydrogenase, photosystem I, and pyridoxal biosynthesis protein PDX1.2 and PDX1.3. The ATP synthase (α, β, and γ) and V-type proton ATPase subunits were down-regulated resulting showed negative impact by Na(+) on the photosynthetic machinery. This ephemeral increase and subsequent decrease in protein contents may demonstrate a counterbalancing influence of identified proteins. Several proteins such as cytochrome b6-f (Cyt b6-f), germin-like-protein, the γ-subunit of ATP synthase, glutamine synthetase, fructose-bisphosphate aldolase, S-adenosylmethionine synthase, carbonic anhydrase were gradually up-regulated during the period of treatment, which can be identified as marker proteins.

The aims of this study were twofold: to examine the empirical evidence supporting the positive contribution that a forest environment can make on human psychological health and well-being and to describe the theoretical framework within which the forest environment has this effect. Our review of the literature provides empirical evidence that a forest experience can contribute to improved emotional and cognitive health.This experience can be through a forest activity program and by experiencing the social and physical conditions of the forest environment and the therapeutic elements of the forest. Visiting or viewing a forest scene has been documented to have a positive effect on psychological healing and well-being in terms of recovering from stress, improving concentration and productivity, improving the psychological state, particularly for people from urban environments. Wilderness and related studies clearly demonstrate that being in a forest environment has a positive effect on people, while results from other studies indicate that contacts with forest environments provide multiple positive physiological and psychological effects on human health that included decreasing the blood pressure and heart rate and reducing anxiety and stress. There are several theories explaining the healing effects of the forest on human beings. Most hypothesize that restorative environments are settings in which recovery is associated with the reduction of stress and that the benefits of contact with natures include a wide range of positive physiological and psychological responses. These theories are based on an evolutionary perspective and share a number of similarities and differences. This article summarizes a number of these theories of restorative environments as well as addresses the current status of forest therapy and the challenges and opportunities for therapeutic effects of the forest in Korea.

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