: A 1-year-old Korean domestic short-haired cat presented with skin hyperextensibility and a severely macerated wound on the skin of the dorsal part of the neck. Diagnostic studies including histopathology and skin extensibility index revealed congenital cutaneous asthenia (Ehlers-Danlos syndrome). In this cat, the skin wounds and defects were successfully managed with standard wound management and cosmetic surgery. Although skin hyperextensibility is persistent, the cat has lived well without other complications to date. To the best of our knowledge, this is the first report of cutaneous asthenia in a cat in Korea.Keywords : cat, cutaneous asthenia, Ehlers-Danlos syndrome, joint laxity, skin hyperextensibility Ehlers-Danlos syndrome (EDS) is a type of inherited cutaneous asthenia, which is caused by collagen production [4]. Although EDS in cats has rarely been reported, inherited EDS has been described in the Himalayan breed, which is similar EDS VIIc in man and dermatosporaxis in calves and sheep [1,10]. Although the EDS is not fatal in cats, it often causes hanging folds of skin, extensive scarring, joint laxity, delayed wound healing with hematoma and hygroma formation [11]. Although the diagnosis is challenging, clinical signs and histopathologic studies of the collagen structure are important to identify this disease. This case study described a rare case of EDS in a Korean domestic short-haired cat.A 1-year-old castrated male Korean domestic short-haired cat weighing 4.2 kg, was presented with severe macerated wound on the skin of dorsal part of neck ( Fig. 1A and B). The cat had medical history of skin maceration by selfscratching and frequent grooming on the abdomen and hind limb. On the physical examination, the skin lesion was consisted of 8.5 × 5.5 cm skin defects by ulcerative wound on the dorsal part of neck ( Fig. 1A and B). The margin of defected skin was necrotized and ulcerative. Skin elasticity was markedly increased (hyperextensibility) on the lesion (Fig. 1). Skin in other body part was also thin and was hyperextensible and fragile ( Fig. 2C and D). Complete blood cell count revealed no particular abnormalities except moderate polycythemia (red blood cell 10.45 M/µL; reference range, 5.5-8.5 M/uL; hematocrit 57.3%; reference range, 37-55%). Serum biochemistry found no particular abnormalities except increased glucose (151 mg/dL; reference range, 60-120 mg/ dL) and decreased albumin (2.7 g/dL; reference range, 3.1-4.1 g/dL).Emergency surgery for covering skin defects of the neck was performed ( Fig. 2A and B). After removal of necrotized wound margin, the skin defected area was covered by extending skin nearby with anchored suture ( Fig. 2A and B). After installing wound drainage, bacterial culture with antibi-*Corresponding author Tel: +82-33-250-8681, Fax: +82-33-244-2367 E-mail: hyun5188@kangwon.ac.kr Fig. 1. Skin lesion of this case. (A and B) The skin lesion was consisted of 8.5 × 5.5 cm skin defects by ulcerative wound on the dorsal part of neck. The margin of defected skin was...

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: An 8-year-old intact male Pekingese (weighing 13 kg) was presented for evaluation of chronic coughing. Thoracic radiography found a redundant tissue swelling (protruded on expiration and collapsed on inspiration) on the ventral neck just cranial to the thoracic inlet. Fluoroscopy also identified that the cranial portion of the right/left cranial lung lobe was seen to protrude through the thoracic inlet into the ventral neck on expiration. On the echocardiogram, there were no abnormal jets in all cardiac valves and no dilation in all cardiac chambers. Based on diagnostic imaging studies, the case was diagnosed as cervical lung lobe herniation.

ABSTRACT. Unusual metastasis of malignant aortic body tumor to multiple bones was detected in a 5-year-old female English Setter dog. Radiographs exhibited an abnormal mass in the base of heart and osteolytic lesions in the bodies of T11 and L2 vertebrates, body of right femur, right proximal humoral epiphysis and infraspinous fossa near to the neck of right scapula. At necropsy, multiple tumor masses of various sizes were observed also in the bones as well as the heart base and tracheobronchial lymph node. Tumor masses of L2 and T11 protruded into the vertebral canal and compressed corresponding sites of spinal cord, leading to paraplegia. Histopathologically, the tumor cells, arranged in sheets or nests, were polyhedral, lightly eosinophilic, finely granular cytoplasm with mostly round to oval nucleus and had scattered bizarre giant cells. Ultrastructural study revealed the characteristic findings that tumor cells contained a large number of small, electron-dense, membrane-limited secretory granules in cytoplasm. This is thought to be an extremely rare case having multiple bone metastases of a malignant aortic body tumor. KEY WORDS: aortic body tumor, canine, multiple bone metastases.J. Vet. Med. Sci. 67(6): 625-627, 2005 Nodular, encapsulated tumors at the base of the heart arise usually from aortic body tissue, ectopic thyroid, or ectopic parathyroid [2,4,5]. Since these tumors had similar properties of gross and histopathology, it should be differentiated [2,4,5]. Ultrastructural characteristics may help to accurately differentiate aortic body tumors, ectopic parathyroid gland tumors, and ectopic thyroid gland tumors originating from tissues at the base of the heart in dogs [2,4,7]. Although malignant aortic body tumors often invade blood vessels, metastasis to the other organs occurs infrequently in dogs [2,4]. As far as we known, multiple bone metastases of malignant aortic body tumor are extremely rare in dogs [1,3,6,7,9].Here we report an unusual case of malignant aortic body tumor with metastasis to multiple bones in an adult female English Setter dog.A 5-year-old female English Setter dog was referred to Chonnam National University Veterinary Teaching Hospital with a history of progressive hindlimb paresis, lethargy and decreased appetite for a four-week duration. Physical examination revealed abnormally accentuated heart sound, mild dehydration, and muscle atrophy of both hindlimbs. Results of the neurologic examination indicated the presence of thoraco-lumbar spinal lesions. Biochemistry and hematology findings were unremarkable. Radiographs of the thorax and spinal column demonstrated a soft tissue mass in the cranial mediastinum displacing the trachea to the right and dorsally, a mild bulging of the left auricle and moth-eaten osteolytic lesions in the L2 vertebrae. A destructive lesion in the right scapula was suspected on the thoracic radiographs, and radiographs of the right shoulder joint were retaken. Osteolytic lesions in the infraspinous fossa near to the neck of right scapula and proxim...

An 8-year-old castrated male Shih Tzu dog (weighing 7.0 kg) presented with anemia and lethargy. Initial diagnosis indicated immune-mediated hemolytic anemia. During therapy, a secondary urinary infection, probably due to the immune suppressive therapy, was diagnosed. Subsequent diagnostic tests, including urinalysis and urine culture, indicated candidal cystitis. Despite ketoconazole therapy for candidal cystitis, the dog died suddenly. A Candida albicans infection was confirmed upon postmortem evaluation. Prolonged immunosuppressive therapy might be the cause of this infection. This is the first case report describing a Candida albicans urinary tract infection accompanied by hemolytic anemia in a dog in Korea.