In MCDA twins with sIUGR, abnormal UA Doppler in the IUGR twin may reflect a more severe unequal placenta share and poorer neonatal outcomes. The prognosis of group II MCDA twins, even with sIUGR found in early gestation, is, by contrast, better.
Significant elevation of leptin can be detected in AF 2 months earlier than the appearance of symptoms; thus, it may be used as a predictive marker for preeclampsia. The increase of these antiangiogenic proteins supports the roles of inflammation and oxidative stress in pathogenesis of preeclampsia.
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