Focused microwave radiometry, aiming mainly in clinical applications at measuring temperature distributions inside the human body, may provide the capability of detecting electrical conductivity variations at microwave frequencies of excitable cell clusters, such as in the case of brain tissues. A novel microwave radiometric system, including an ellipsoidal conductive wall cavity, which provides the required beamforming and focusing, is developed for the imaging of biological tissues via contactless measurements. The measurement is realized by placing the human head in the region of the first focus and collecting the radiation converged at the second by an almost isotropic dipole antenna connected to a sensitive radiometer operating at 3.5 GHz. In order to compute the focusing properties of the ellipsoidal reflector, an accurate electromagnetic numerical analysis is developed using a semianalytical method. The experimental part of this study focuses on measurements of activation of the primary somatosensory (SI) brain area, elicited during the application of the cold pressor test, a standard experimental condition inducing pain. Analysis of the measured data from 16 healthy subjects suggests that this methodology may be able to pick up activation of the SI during the pain conditions as compared with the nonpainful control conditions. Future research is needed in order to elucidate all the interacting factors involved in the interpretation of the presented results. Finally, potential limitations to the generalization of our results and strategies to improve the system's response are discussed.Index Terms-Activation of primary somatosensory (SI) cortex, ellipsoidal conductive wall cavity, focused microwave radiometry, imaging of conductivity variations in biological tissues.
Auditory event-related potentials (AERP) were elicited in 68 epileptic patients and 30 age-matched controls. Epileptic patients had significantly prolonged N2 and P300 (P3) latencies compared with controls. Seven patients were above the range of 3 standard deviations from the control mean values. Amongst epileptics, patients with temporal lobe epilepsy had significantly prolonged P3 latencies compared to patients with idiopathic generalized epilepsy. Patients with abnormal EEGs had significantly prolonged P3 latencies compared to those with normal EEGs. Patients on anticonvulsant monotherapy had shorter P3 latencies, compared to patients taking a combination of two or more anticonvulsants. Patients on shorter duration of treatment had less prolonged P3 latencies compared to those on longer anticonvulsant treatment.
The present study assessed the effects of a diet and exercise intervention in jockeys on body composition, metabolism, bone and mental health. 10 jockeys followed an individually prescribed 6-wk diet (Carbohydrate=2.5-3.5 g/kg, Protein=2.5 g/kg, Fat=1.0 g/kg). Body mass (59.2±4.6 vs. 57.6±4.5 kg), fat mass (7.5±3.5 vs. 6.2±2.6) and body fat (13.1±5.9 vs. 11.5±4.9%) all decreased (P<0.05) from pre to post-intervention whilst lean mass (47.1±5.3 vs. 47.0±5.5 kg) was maintained (P=0.80). RMR (1703±329 vs. 1975±313 kcal.d(-1)), VO2max (3.8±0.8 vs. 4.1±0.7 L/min(- 1)) chest strength (65±11 vs. 71±13 kg), leg strength (160±28 vs. 175±29 kg) and jumping height (40±6 vs. 48±5 cm) significantly increased (P<0.05). Bone health (DXA) did not change (P>0.05) at hip (-1.04±1.29 vs. - 0.76±0.71) or lumbar sites (-1.32±0.76 vs. - 1.31±0.77). Psychometrics (GHQ-12 and EAT-26) remained unchanged (10.3±4.3 vs. 8.9±3.8 and 14.8±9.6 vs. 11.0±5.6, P>0.05, respectively). This approach represents a marked difference from jockeys' habitual weight-making that largely involves dehydration and food deprivation.
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