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Lactic acid (40 mg.) and its precursor (32 mg.) are thus seen to account for 73% of the muscle glycogen which disappears in 30 minutes after the epinephrine injection. Since a deposition of liver glycogen from blood lactic acid occurs shortly after the injection, part of the remaining 28 mg. is probably accounted for by this process.A decrease in the inorganic phosphates of the blood has also been observed after insulin injections.s Since muscle glycogen increases under these conditions, it seems possible that the same chemical transformations occur as after epinephrine injections but in the opposite direction. This is being investigated at the present time.