IntroductionVancomycin is a recognised cause of drug-induced acute kidney injury (AKI).ObjectiveThe aim of this systematic review was to summarise the incidence of, and the risk factors for, vancomycin-associated AKI (v-AKI) in children.DesignA systematic search was performed in November 2020 on the search engines PubMed, Web of Science and Medline, using predefined search terms. The inclusion criteria were primary paediatric studies, intervention with vancomycin and studies that included AKI as an outcome. Study quality was assessed using the relevant Critical Appraisal Skills Programme checklist. The data are reported using descriptive statistics.Results890 studies were identified and screened with 25 studies suitable for inclusion. A cohort of 12 730 patients with v-AKI were included and the incidence of v-AKI in children was found to be 11.8% (1.6%–27.2%). The median age of the cohort was 2.5 years (range 0–23) and 57% were male patients. Risk factors that increased the likelihood of v-AKI were concomitant use of nephrotoxic medications, increased trough concentrations and, to a lesser extent, increased dose, longer duration of treatment, impaired renal function and if the patient required paediatric intensive care.ConclusionsThe incidence of v-AKI in children is significant and methods to reduce this risk should be considered. Further prospective interventional studies to understand the mechanisms of nephrotoxicity from vancomycin are needed and targeting risk factors may make vancomycin administration safer.

Conclusion Conclusion:There needs to be a coordinated effort between patients and professionals, to understand how CKD education should be more integrated at point of care, and public health.

In each subgroup there were 3 roles; storyteller, listener, and an observer who would take notes on the interaction. These would rotate every 10 minutes.Once everyone had related their stories the group would reconvene to discuss and collate themes in a section facilitated by a psychologist. Avenues of communication were available post-session via email and a survey to get in touch with the faculty regarding any outstanding issues. All information gathered was confidential. Results Themes collected centred on persistent low morale, feelings of helplessness, uselessness and dread. All tallied well with issues we know affect existing and putative paediatric trainees.Conclusions Results indicate that attendees found the forum a useful and open place to share their experiences, and that that this would be valuable as a regular event in the paediatric calendar, particularly with the additional stress placed on clinicians with redeployment. As such, we hope to present a replicable session template which can be adopted by other departments and hospitals. Through increased adoption and feedback the template could be improved to best fit those making use of the sessions.